Camera-based radiotherapy dosimetry using dual-material 3D printed scintillator arrays.

Purpose And Objective: To describe a methodology for the dual-material fused deposition modeling (FDM) 3D printing of plastic scintillator arrays, to characterize their light output under irradiation using an sCMOS camera, and to establish a methodology for the dosimetric calibration of planar array geometries.

Materials And Methods: We have published an investigation into the fabrication and characterization of single element FDM printed scintillators intending to produce customizable dosimeters for radiation therapy applications. This work builds on previous investigations by extending the concept to the production of a high-resolution (scintillating element size 3 × 3 × 3 mm ) planar scintillator array.

Characterization of novel 3D printed plastic scintillation dosimeters.

We propose a new methodology for the fabrication and evaluation of scintillating detector elements using a consumer grade fusion deposition modeling (FDM) 3D printer. In this study we performed a comprehensive investigation into both the effects of the 3D printing process on the scintillation light output of 3D printed plastic scintillation dosimeters (PSDs) and their associated dosimetric properties. Fabrication properties including print variability, layer thickness, anisotropy and extrusion temperature were assessed for 1 cm printed samples.

Fabrication and characterization of a stemless plastic scintillation detector.

Purpose: To fabricate a stemless plastic scintillation detector (SPSD) and characterize its linearity and reproducibility, and its dependence on energy and dose per pulse; and to apply it to clinical PDD and output factor measurements.

Methods: An organic bulk heterojunction photodiode was fabricated by spin coating a blend of P3HT and PCBM onto an ITO-coated glass substrate and depositing aluminum top contacts. Eljen scintillators (~5 × 5 × 5 mm ; EJ-204, EJ-208, and EJ-260) or Saint-Gobain scintillators (~3 × 3 × 2 mm ; BC-400 and BC-412) were placed on the opposite side of the glass using a silicone grease (optical coupling agent) creating the SPSD.

Radiochromic film in vivo dosimetry predicts early the risk of acute skin toxicity for brachytherapy partial breast irradiation.

Brachytherapy accelerated partial breast irradiation (APBI) is well tolerated, but reported acute toxicities including moist desquamation rates range from 7% to 39%. Moist desquamation is correlated to long-term skin toxicity and high skin dose is the main risk factor. This study uses radiochromic films for in vivo skin dosimetry of low dose rate (LDR) APBI brachytherapy and prediction of skin toxicity.

Energy-dependent OAR sparing and dose conformity for total marrow irradiation of obese patients.

Purpose: To investigate the effect on target coverage and organs at risk sparing by using 10 versus 6 MV for VMAT total marrow irradiation of obese patients.

Methods And Materials: Twenty-six total marrow irradiation, TMI, treatment plans delivered between December 2014 and June 2017 were reviewed and 10 were chosen for replanning based on patient characteristics and plan metrics. Beam geometry and isocenter placement were conserved, energy was changed from 6 to 10 MV and plans were reoptimized.