Interleukin-15 are associated with insulin resistance in postmenopausal women with metabolic syndrome.

Objective: To determine if higher levels of circulating interleukin (IL)-15 are positively associated with improvement in insulin resistance in postmenopausal women (PW) with metabolic syndrome (MS).

Methods: According to the median value of IL-15 at baseline, PW older than or equal to 45 years were divided into two groups: higher ( = 43) and lower ( = 42) IL-15. There was a 9-month follow-up period with clinical assessments at baseline and at 9 months (criteria of metabolic syndrome, body fat, and insulin resistance).