Vaginal pessary in advanced pelvic organ prolapse: impact on quality of life.

Introduction And Hypothesis: Pelvic organ prolapse (POP) is a highly prevalent dysfunction of the pelvic floor affecting up to 40% of women. The symptoms of POP have a major impact on quality of life. Pessary treatment is a therapy option associated with high levels of satisfaction and few complications.

Copaiba oil effect under different pathways in mice subjected to sepsis.

Purpose: To evaluate the effects of copaiba oil administered by different routes on survival of mices subjected to cecal ligation and puncture.

Methods: Thirty two mice were distributed into four study groups (N=8): Sham group: normal standard animals;

Control Group: submitted a cecal ligation and puncture (CLP); Gavage group: submitted a CLP, and treat with copaiba oil by gavage; and Subcutaneous group: submitted a CLP, and treat with copaiba oil by subcutaneous injection. After the death of the histological analysis were performed.