Coronary computed tomography plaque-based scores predict long-term cardiovascular events.

Objectives: Coronary computed tomography angiography (coronary CTA) scores based on luminal obstruction, plaque burden, and characteristics are used for prognostication in coronary artery disease (CAD), such as segmental stenosis and plaque extent involvement and Gensini and Leaman scores. The use of coronary CTA scores for the long-term prognosis remains not completely defined. We sought to evaluate the long-term prognosis of CTA scores for cardiovascular events in symptomatic patients with suspected CAD.

Diminished cholesterol efflux mediated by HDL and coronary artery disease in young male anabolic androgenic steroid users.

Background And Aims: Anabolic androgenic steroids (AAS) have been associated with coronary artery disease (CAD). AAS abuse leads to a remarkable decrease in high-density lipoprotein (HDL) plasma concentration, which could be a key factor in the atherosclerotic process. Moreover, not only the concentration of HDL, but also its functionality, plays a pivotal role in CAD.

On the search of arterial geometry heritability.

Background: Geometrical risk factors for CAD have been previously proposed before. To date, however, the effect of those factors is not conclusive, and remains as an open research field. Here, we hypothesize that some of these factors have a genetic component explaining inter-individual variability.