Phenotypes of Dialysis-Requiring Acute Kidney Injury and Associations with Mortality in a South American Population.

Key Points: Comprehensive analysis of 17,158 patients with dialysis-requiring AKI in Brazil, uncovering intricate etiological patterns and outcomes across all age groups. Detailed latent class analysis reveals four distinct phenotypes for patients with dialysis-requiring AKI, each with unique clinical characteristics and mortality risks. The study underscores the necessity of age-specific AKI management strategies, informed by diverse etiologies and survival outcomes across the lifespan.

Socioeconomic Influences on the Outcomes of Dialysis-Requiring Acute Kidney Injury in Brazil.

Introduction: Although research suggests that socioeconomic deprivation is linked to a higher incidence of acute kidney injury (AKI) and worse outcomes in high-income countries, there is limited knowledge about these epidemiologic factors in developing countries. In addition, the impact of medical institution administration (private versus public) on AKI outcomes remains to be determined.

Methods: We studied 15,186 pediatric and adult patients with dialysis-requiring AKI (AKI-D) admitted to private and public hospitals in Rio de Janeiro, Brazil.