Effect of a constant rate infusion of ketamine on left ventricular systolic and diastolic function in dogs anesthetized with propofol.

Objective: To evaluate the effect of a constant rate infusion of ketamine on left ventricular systolic and diastolic function in dogs anesthetized with propofol.

Study Design: Prospective randomized, blinded clinical study.

Animals: Sixteen healthy dogs.

Hemodynamic Assessment via Echocardiography During Propofol Anesthetic Induction in Healthy Dogs.

Propofol is an intravenous anesthetic administered as a bolus or continuous infusion during anesthetic induction and maintenance. Its pharmacokinetic characteristics include hepatic and extrahepatic metabolism with a rapid onset of action and short duration, which provides a smooth anesthetic induction without excitatory effects. To evaluate whether the isolated use of propofol in anesthetic induction in dogs changes the hemodynamic variables assessed via echocardiography.