Biological and physical properties of calcium hydroxide-based pulp-capping materials and their modifications.

Purpose: To evaluate the biological and physical properties of calcium hydroxide-containing pulp-capping materials and their modifications with different solutions and antioxidant Resveratrol (RES) addition.

Methods: Calcium hydroxide+distilled-water:C, calcium hydroxide+saline:S, calcium hydroxide+synthetic tissue fluid:STF, Dycal:D, calcium hydroxide+distilled-water+RES:C+RES, calcium hydroxide+saline+RES:S+RES, calcium hydroxide+synthetic tissue fluid+RES:STF+RES, Dycal+RES:D+RES were tested. Cytotoxicity was determined by WST-1.

Dental Implants and Implant Coatings: A Focus on Their Toxicity and Safety.

Dental implants are medical devices that are surgically inserted into the patient's jawbone by an orthodontist to act as roots of missing teeth. After the implantation, the maxilla or mandible integrates with the surface of the dental implant. This process, called "osseointegration," is an important period to ensure the long-term use of dental implants and prevent implant failures.

The effects of extended polymerization time for different resin composites on reactive oxygen species production and cell viability.

Purpose: The present study was conducted to determine oxidative stress and cell viability after contact with resin composites polymerized for different times.

Methods: Disk-shaped specimens of Admira Fusion, Ceram X One Universal, Solare x and Filtek Z550 (n = 12) were prepared, and two subgroups with polymerization times of 20 and 40 s were employed. The specimens were incubated with mouse fibroblast cells for 48 and 72 h, and changes in reactive oxygen species (ROS) production and cellular viability were determined by an assay with a cell-permeable fluorescent dye, 2',7'-dichlorodihydrofluorescein diacetate (HDCF-DA), and the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay, respectively.

Targeted next-generation sequencing as a diagnostic tool in gastrointestinal system cancer/polyposis patients.

Background: Recent advances in next-generation sequencing (NGS) technology have enabled multigene testing and changed the diagnostic approach to hereditary gastrointestinal cancer/polyposis syndromes. The aim of this study was to analyze different cancer predisposition genes in hereditary/sporadic gastrointestinal cancer/polyposis.

Methods: Cancer predisposition genes were analyzed with an Illumina MiSeq NGS system in 80 patients with gastrointestinal cancer/polyposis who were examined between the years 2016 and 2019.

The improvement of biocompatibility of adhesives : The effects of resveratrol on biocompatibility and dentin micro-tensile bond strengths of self-etch adhesives.

Objective: The aim of this in vitro study is to evaluate the effects of resveratrol (RES) addition on the cytotoxicity and microtensile bond strength (μTBS) of different adhesives.

Materials And Methods: Five self-etching adhesives (G-aenial Bond-GC, Optibond All in One-Kerr, Gluma Self Etch-Kulzer, Clearfil S Bond-Kuraray, and Nova Compo-B Plus-Imicryl) were tested. They were applied to L-929 cell culture by the extract method.

Procrastination and predictor variables among a group of dental students in Turkey.

The aim of this study was to assess the prevalence of procrastination among a group of Turkish dental students and to determine the predictors and consequences of procrastination. A total number of 273 females and 179 males (aged between 18 and 28) were included in the study. Tuckman procrastination scale, Academic Life Satisfaction Scale, Concern over Mistake Scale, Poor Time Management Scale, Self-Doubt Scale, Irrational Beliefs about Studying Scale, Positive and Negative Affect Schedule and Life Satisfaction Scale were used to gather data.

In vivo performance of different scaffolds for dental pulp stem cells induced for odontogenic differentiation.

This study was designed to determine the in vivo performance of three different materials as scaffolds for dental pulp stem cells (DPSC) undergoing induced odontogenic differentiation. An odontogenic medium modified by the addition of recombinant human bone morphogenetic protein 2 was used in the experimental groups to induce differentiation. Mesenchymal stem cell medium was used in the control groups.

A 3-year randomized clinical trial evaluating two different bonded posterior restorations: Amalgam versus resin composite.

Objective: To compare the performance and postoperative sensitivity of a posterior resin composite with that of bonded amalgam in 40 (n = 20) large sized cavities and to evaluate whether resin composite could be an alternative for bonded amalgam.

Materials And Methods: This was a randomized clinical trial. Twenty patients in need of at least two posterior restorations were recruited.

Medium modification with bone morphogenetic protein 2 addition for odontogenic differentiation.

The aim of this study was to evaluate whether medium modification improves the odontogenic differentiation of human dental pulp stem cells (DPSC) in vitro and in vivo. DPSC isolated from human impacted third molar teeth were analysed for clusters of differentiation with flow cytometry. Odontogenic differentiation was stimulated by medium modification with the addition of bone morphogenetic protein 2 (BMP2).

The protective effect of resveratrol against dentin bonding agents-induced cytotoxicity.

This study was designed to evaluate the cytotoxicity of four dentin bonding agents and the effects of an antioxidant addition. Group A: G-aenial Bond, Group B: Optibond All in One, Group C: Gluma Self Etch and Group D: Clearfil S(3) Bond were added to the medium using extract method. The cells were cultured with or without resveratrol (RES) addition.

The prevalence and consequences of burnout on a group of preclinical dental students.

Objective: The aim of this study is to investigate the prevalence of burnout among a group of Turkish preclinical dental students, to compare the level of burnout and to determine the consequences in structural equation model.

Materials And Methods: Preclinical dental students (n = 329, 50.5% of females and 49.

Does post-bleaching fluoridation affect the further demineralization of bleached enamel? An in vitro study.

Background: Topical fluoride agents have been shown to be the most effective method in treating demineralized enamel after in-office bleaching treatments. Thus, this study aimed to examine the effects of two different post-bleaching fluoridation agents: 1.5% titanium tetrafluoride (TiF(4)) (9200 ppm) and 2.

Replantation after traumatic avulsion.

The aim of this report is to present the case of an accidentally avulsed maxillary central incisor kept in saline solution from the moment of trauma until its replantation 3 h later in a 13-year-old girl. The avulsed tooth was replanted back into the alveolar socket and splinted with composite resin. Calcium hydroxide intracanal dressing was used to prevent inflammatory root resorption.

Susceptibility of enamel treated with bleaching agents to mineral loss after cariogenic challenge.

Objectives. Controversial reports exist whether bleaching agents cause a susceptibility to demineralization. The aim of this study was to compare the calcium loss of enamel treated with different bleaching agents and activation methods.

An unusual case of immediate hypersensitivity reaction associated with an amalgam restoration.

This report describes a case of immediate hypersensitivity reaction associated with the mercury component of amalgam restorations. The release of mercury induced an acute reaction which resulted in erythematous lesions, severe burning and itchy sensation and difficulty in breathing. Skin patch test results indicated a very strong positive reaction to mercury.

Effect of bleaching agents on calcium loss from the enamel surface.

Objectives: To compare the Ca2+ loss of enamel treated with 38% hydrogen peroxide (HP), 35% HP with light, and 10% carbamide peroxide (CP).

Method And Materials: Ten extracted premolars were sectioned buccolingually and longitudinally so that 4 specimens were obtained from each tooth. The specimens were randomly assigned to 1 of 4 groups to receive the following bleaching agents: 38% HP, 35% HP with light, 10% CP, and no agent (control).

Fluoride release from esthetic restorative materials with and without adhesive.

Objective: The purpose of this in vitro study was to compare the effect of surface coating containing fluoride on patterns and amounts of fluoride release from 5 esthetic restorative materials.

Method And Materials: Twelve cylinders of each material were prepared in a plexiglass mold. The experimental groups (n = 6) were coated with 1 layer of fluoridated adhesive resin, Prompt L-Pop, while the control groups (n = 6) remained uncoated.

Clinical evaluation of indirect resin composite and ceramic onlays over a 24-month period.

The purpose of this study was to compare the clinical performance of ceramic and indirect resin composite onlays over a 24-month period. A total of 94 onlay restorations in 47 patients were included in this study. Cavities were prepared, full-arch impressions were taken, and onlays were fabricated in the laboratory.

A validated cold vapour-AAS method for determining mercury in human red blood cells.

A cold vapour-atomic absorption spectrometry (CV-AAS) method for determining mercury in dental students and clinical teaching staff red blood cells at a dental school using amalgam as a restorative material has been validated. A number of blood samples (n = 122) from dental students in years I to V, clinical teachers in restorative dentistry and controls were collected and analysed. Accuracy, linearity, precision (repeatability and reproducibility) and robustness of the method have been determined, and detection and quantification limits have been calculated.

Effects of topical fluoride agents on artificial enamel lesion formation in vitro.

Objective: The purpose of this study was to assess the effects of topical fluoride agents on enamel erosion in vitro.

Method And Materials: Ten premolars extracted for orthodontic purposes were sectioned buccolingually and then longitudinally into two parts, so that four specimens were obtained from each tooth. The specimens were randomly assigned to one of four groups.

Blood mercury levels of dental students and dentists at a dental school.

Objective: To determine the blood mercury levels in dental students and clinical teaching staff in a dental school using amalgam as a restorative material.

Setting: A dental school in Ege University, Turkey surveyed during one academic year.

Subjects And Methods: Cross-sectional study of groups of dental students (n=92) in years I to V, clinical teachers in restorative dentistry (n=16) and controls (n=14).

The penetration of root canal sealers into dentinal tubules. A scanning electron microscopic study.

The purpose of this study was to evaluate the effect of smear layer on penetration of four root sealers into dentinal tubules. Sixty-four, recently extracted, human maxillary and mandibular incisors were used. Following removal of the crowns, the pulps were extirpated and the root canals instrumented.

A comparative sealability study of different retrofilling materials.

The purpose of this study was to compare the sealing ability of high-copper amalgam, glass ionomer cement, and silver glass ionomer cement as retrofilling materials when used with and without varnish. Seventy extracted human single-rooted anterior teeth were instrumented and the root canals obturated with laterally condensed gutta-percha and sealer. The apical 3 mm of each root was resected and a 2 mm-deep apical Class I preparation cut.