Publications by authors named "Tew Hong Ho"
Ovarian clear cell carcinoma (CCC) has an East Asian preponderance. It is associated with endometriosis, a benign condition where endometrial (inner lining of the uterus) tissue is found outside the uterus and on the peritoneal surface, in the abdominal or pelvic space. CCC is relatively more resistant to conventional chemotherapy compared to other ovarian cancer subtypes and is associated with a poorer prognosis.
View Article and Find Full Text PDFMucinous epithelial ovarian cancer has a poor prognosis in the advanced stages and responds poorly to conventional chemotherapy. We aim to elucidate the clinicopathological factors and incidence of HER2 expression of this cancer in a large Asian retrospective cohort from Singapore. Of a total of 133 cases, the median age at diagnosis was 48.
View Article and Find Full Text PDFWe present a case series of four patients with Caesarean scar pregnancies (CSPs) managed at our gynaecological unit between October 2008 and May 2009. Three patients were detected while asymptomatic, and were treated with elective intragestational sac methotrexate injections. The last patient had presented following complications from a termination of pregnancy for a CSP that was misdiagnosed as intrauterine.
View Article and Find Full Text PDFBackground: In 2008, the Federation of Gynecology and Obstetrics (FIGO) revised their 1988 staging system for uterine leiomyosarcomas. In this article, we compare performance of the 2008 and 1988 FIGO systems.
Methods: Individual case data were manually culled.
Article Synopsis
- This study analyzed the survival outcomes and failure patterns in 120 patients with locally advanced cervical cancer treated with high-dose rate brachytherapy and cisplatin-based chemoradiotherapy from 1999 to 2005.
- The 5-year overall survival rate was 65%, while the disease-free survival rate was 57.3%, with most recurrences occurring at distant sites.
- Significant factors impacting survival included low hemoglobin levels and tumor size, highlighting the need for further research on the safety of this treatment combination and the importance of imaging for assessing prognosis.
Introduction: Pathologically adherent placentas occur when there is a defect of the decidua basalis, typically arising from previous caesarean section, resulting in abnormally invasive implantation of the placenta. The depth of placental invasion varies from the superficial (accreta), to transmural and possibly beyond (percreta).
Clinical Picture: We report on 2 cases, one treated "conservatively", the other with a caesarean hysterectomy, both of which led to a safe outcome for both mother and baby.