Distal transradial versus conventional transradial access in acute coronary syndrome.

Objective: Distal transradial access (TRA) has been recently introduced as an alternative access site for coronary angiography (CAG). Both procedures can be performed in cardiology clinics by interventional cardiologists. Although distal TRA is considered to be more difficult as it requires artery puncture and experienced cardiologists, it seems to be more advantageous because of the limited risk of arterial occlusion.

The Effects of Cigarette Smoking on the Tp-e Interval, Tp-e/QT Ratio and Tp-e/QTc Ratio.

Background: Cigarette smoking increases the risk of sudden cardiac death. Smoking may predispose individuals to ventricular fibrillation and sudden cardiac death by altering ventricular repolarization and stimulating sympathetic nervous system activity.

Objectives: The aim of the study was to investigate the instantaneous effects of smoking on ventricular repolarization.

S100A1 as a Potential Diagnostic Biomarker for Assessing Cardiotoxicity and Implications for the Chemotherapy of Certain Cancers.

This study examined the value of blood marker S100A1 in detecting cardiotoxicity induced by chemotherapy agents; trastuzumab and lapatinib, in normal rat heart. The rats were divided into three groups: control (n = 8, no treatment), T (n = 8, one time ip treatment with 10 mg/kg trastuzumab) and L (n = 8, oral treatment with 100 mg/kg/day lapatinib for 7 days). The activities of oxidative stress parameters Malondialdehyde (MDA), Superoxide dismutase (SOD), Catalase (CAT) and Glutathione (GSH) were measured from the extracted cardiac tissues.

Severity of coronary artery disease and echocardiographic parameters of ventricular diastolic function.

Objective: The objective of this study was to determine the relation between the severity of the coronary artery disease (CAD) and left ventricular (LV) diastolic function in patient with stable CAD and normal LV ejection fraction.

Methods: Sixty patients with stable CAD were included in the study. All angiographic variables pertinent to SYNTAX Score (SS) and Gensini score (GS) calculation were computed by two experienced interventional cardiologists.

QT dispersion during hypobaric hypoxia.

Objective: Hypoxia is one of the major concerns in aviation. Clinical hypoxia has been shown to increase QT dispersion (QTd). We aimed to examine QTd during hypobaric chamber training to observe the effect of hypobaric hypoxia on QT dispersion.