Dynamic changes in insulin requirements with post-operative time using bedside artificial pancreas to maintain normoglycemia without hypoglycemia after cardiac surgery.

It is difficult to manage postoperative blood glucose levels without hyperglycemia and hypoglycemia in cardiac surgery patients even if continuous intravenous insulin infusion is used. Therefore, the insulin requirements for maintaining normoglycemia may be difficult to evaluate and need to be elucidated. In this single-center retrospective study, 30 adult patients (age 71.

Utility of bedside artificial pancreas for postoperative glycemic control in cardiac surgery.

Unlabelled: Perioperative hyperglycemia, hypoglycemia, and high glycemic variability are independent risk factors for mortality in critically ill patients. After cardiac surgery, intensive glycemic control without hypoglycemia may help to reduce the number of adverse events; however, postoperative glycemic control is difficult in many cases. In this study, we investigated whether the bedside artificial pancreas STG-55 is useful for postoperative glycemic control in cardiac surgery.

Genomic structure of the rat and mouse histamine N-methyltransferase gene.

Northern blotting analysis revealed different tissue distribution patterns of HMT mRNA between mice and rats. In the mouse, mRNA expression was detected in the brain, kidney and liver. In the rat, there was an extremely high mRNA signal only in the kidney.