Publications by authors named "Tetsuya Kita"

Background: To evaluate antibody responses against the primary series of vaccination of severe acute respiratory syndrome coronavirus-2 [SARS-CoV-2] vaccines in the staff and residents of Japanese geriatric intermediate care facilities.

Methods: All subjects (159 staff and 96 residents) received two doses of the BNT162b2 mRNA vaccine 3 weeks apart. Baseline data of subject were collected using a structured form.

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Article Synopsis
  • The study aimed to understand the incidence and risk factors for norovirus-related diarrhea among elderly residents in Japanese geriatric intermediate care facilities.
  • Conducted from November 2018 to April 2020, the study followed 1,727 residents across 10 facilities, finding that 74 developed diarrhea, with 13 testing positive for norovirus—resulting in an incidence rate of 10.11 per 1000 person-years.
  • Key risk factors for developing norovirus-related diarrhea included a higher care-needs level, hypertension, stroke, and using a cane, indicating a correlation between health conditions and susceptibility to this infection in elderly populations.
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Less invasive methods for treating dental caries are strongly desired. However, conventional dental lasers do not always selectively remove caries or ensure good bonding to the composite resin. According to our previous study, demineralized dentin might be removed by a nanosecond pulsed laser operating at wavelengths of around 5.

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Article Synopsis
  • Conventional dental lasers struggle with selective caries removal and good bonding with composite resin, highlighting the need for less invasive methods.
  • A study found that using a nanosecond pulsed laser at specific wavelengths (5.75 and 5.80 μm) can effectively remove demineralized dentin without damaging healthy areas.
  • These optimal laser conditions also promote better bonding strength with composite resin compared to traditional lasers, making this approach a promising option for less invasive dental caries treatment.
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An 80-year-old woman with type 2 diabetes was admitted due to right-handed muscle weakness. The patient presented with Brown-Sequard syndrome, with complete paralysis of the right lower limb along with a loss of pain and temperature sensations in the left lower limb. Magnetic resonance imaging revealed a cervical epidural abscess, and accompanying edema or inflammation of the right side of the spinal cord at the C5 level.

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[structure: see text] Crambescidin 359 (4), which is the "vessel part" of the pentacyclic guanidine alkaloid ptilomycalin A (1), was synthesized for the first time based upon successive 1,3-dipolar cycloaddition reaction. This synthesis established the absolute stereochemistry of 4.

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