Publications by authors named "Tetsuya Isayama"
Birth weight and head circumference for 22-29 weeks gestation neonates from an international cohort.
Arch Dis Child Fetal Neonatal Ed
January 2025
Objective: Size at birth is a key indicator of in utero growth. Our objective was to generate sex-specific percentiles for birth weight and head circumference in neonates born between 22 and 29 weeks gestation from pregnancies without hypertension or diabetes and assess differences between vaginal and caesarean births and between singletons and twins.
Methods: We used data from 12 countries participating in the International Network for Evaluating Outcomes in Neonates database from 2007 to 2021.
Introduction: Type 1 congenital pulmonary airway malformation (CPAM) is characterized by large, dilated cysts that rapidly expand due to aeration immediately after birth, often necessitating surgical resection. In atypical cases of CPAM type 1, fetal T2-weighted magnetic resonance imaging (MRI) reveals a low-intensity solid lung mass containing multiple irregular T2 high-intensity areas.
Methods: Data were retrospectively collected for infants with atypical CPAM type 1 born at our hospital between March 2002 and December 2022.
Objectives: To investigate the effectiveness of placing an indicator light indicating inadequate ventilation near the face mask during positive-pressure ventilation with respiratory function monitors (RFMs) in neonatal resuscitation. The study is a three-group, randomised, controlled, crossover simulation trial.
Methods: Paediatrics residents, neonatology fellows, and attending neonatologists at a single neonatal intensive care unit.
Article Synopsis
- The eighth annual summary from the International Liaison Committee on Resuscitation (ILCOR) focuses on the latest findings in cardiopulmonary resuscitation (CPR) and emergency cardiovascular care, building on a comprehensive review from 2020.
- This summary is based on the evaluation of recent resuscitation evidence by experts from six different ILCOR task forces, who utilized specific criteria to assess the quality of evidence and reached consensus treatment recommendations.
- The document also identifies key areas where more research is needed, sharing insights into the task forces’ discussions through sections like Justification and Evidence-to-Decision Framework Highlights.
This is the eighth annual summary of the International Liaison Committee on Resuscitation International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations; a more comprehensive review was done in 2020. This latest summary addresses the most recent published resuscitation evidence reviewed by the International Liaison Committee on Resuscitation task force science experts. Members from 6 International Liaison Committee on Resuscitation task forces have assessed, discussed, and debated the quality of the evidence, using Grading of Recommendations Assessment, Development, and Evaluation criteria, and their statements include consensus treatment recommendations.
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- The project aims to reduce neonatal deaths in premature infants, particularly very low birth weight (VLBW) infants, in low- and middle-income countries by forming an international collaboration called AsianNeo with various Asian countries.
- AsianNeo includes nine neonatal networks from countries like Indonesia, Japan, and South Korea, and will conduct four main studies focused on assessing resources, outcomes, and quality improvements in neonatal care.
- The study has received ethical approval and will share findings through educational programs, conferences, and medical journals to enhance neonatal care quality across the participating countries.
Background: Although furosemide is used during cyclooxygenase (COX) inhibitor therapy for patent ductus arteriosus (PDA), there are concerns regarding increased ductal closure failure and acute renal failure (ARF). This systematic review explores the effects of furosemide during COX inhibitor therapy.
Methods: We searched MEDLINE, Embase, Cumulative Index to Nursing and Allied Health Literature, Cochrane Central Register of Controlled Trials, and Igaku Chuo Zasshi databases for randomized clinical trials that assessed furosemide during COX inhibitor therapy for PDA in preterm infants.
Inter-hospital variations in the respiratory outcomes of very and extremely pre-term infants: A cohort study in Japan.
Paediatr Perinat Epidemiol
November 2024
Background: Hospital-level and international variations exist in the management strategies of bronchopulmonary dysplasia (BPD). However, studies evaluating hospital-level variations in the respiratory outcomes of pre-term infants associated with differing management strategies of BPD are lacking.
Objective: Herein, we aimed to assess inter-hospital variations in the respiratory outcomes of BPD in very pre-term and extremely pre-term infants.
Background: Limited evidence exists regarding children receiving home healthcare devices (HHDs). This study aimed to describe the range and type of HHD use by children with chronic medical conditions in Japan and explore factors leading to increased use of these devices.
Methods: This retrospective cohort study was conducted using data from the National Database of Health Insurance Claims and Specific Health Checkups of Japan.
Introduction: Despite advances in neonatal care, late-onset sepsis remains an important cause of preventable morbidity and mortality. Neonatal late-onset sepsis rates have decreased in some countries, while in others they have not. Our objective was to compare trends in late-onset sepsis rates in 9 population-based networks from 10 countries and to assess the associated mortality within 7 days of late-onset sepsis.
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- The study evaluated the long-term outcomes and risk factors associated with renal oligohydramnios in fetuses from 2002 to 2023, involving 131 cases.
- Findings indicated that significant percentages of cases resulted in pregnancy termination, intrauterine fetal death, neonatal death, and postneonatal death, with survival rates of 30%.
- Key risk factors identified for fetal and postneonatal death included earlier gestational age at oligohydramnios onset and low birth weight, emphasizing the importance of risk assessment for better outcomes.
Background: Bronchopulmonary dysplasia (BPD) persists as one of the foremost factors contributing to mortality and morbidity in extremely preterm infants. The effectiveness of administering sildenafil early on to prevent BPD remains uncertain. The aim of this study was to investigate the efficacy and safety of prophylactically administered sildenafil during the early life stages of preterm infants to prevent mortality and BPD.
View Article and Find Full Text PDFSurvival and unique clinical practices of extremely preterm infants born at 22-23 weeks' gestation in Japan: a national survey.
Arch Dis Child Fetal Neonatal Ed
December 2024
Article Synopsis
- The study aimed to assess the treatment and outcomes for infants born at 22-23 weeks' gestational age (wkGA) in Japan, using data collected from a national survey in September 2021.
- Out of 295 Neonatal Intensive Care Units (NICUs), 255 responded, with 145 specifically caring for these premature infants, revealing that a majority actively resuscitated 22 wkGA infants and had high survival rates post-resuscitation.
- The survey also identified distinct clinical practices in Japan for managing these infants, such as unique delivery methods, immediate medical interventions, and preventive care strategies aimed at improving their outcomes.
Aim: For women, being underweight increases their susceptibility to osteoporosis, anemia, and other conditions and affects the weight of their infants and the well-being of future generations. This study examined the association between low pre-pregnancy body mass index (BMI) and low birthweight using health insurance claims data and health checkup data, including weight measurements.
Methods: We used health insurance claims data and health checkup data (JMDC, Tokyo, Japan) of women and their newborns in Japan between 2006 and 2020.
Introduction: A feature of the management of extremely preterm infants in Japan is proactive circulatory management using early routine echocardiography performed by neonatologists.
Methods: This study was a post hoc analysis of the Patent ductus arteriosus and Left Atrial Size Evaluation in preterm infants (PLASE) study, which is a prospective cohort study including preterm infants admitted to 34 tertiary neonatal intensive care units in Japan between October 2015 and December 2016. We described the details of the treatment strategy of patent ductus arteriosus (PDA) based on early routine echocardiography.
Background: Erythropoietin has an angiogenic effect on the retina and might increase the risk of retinopathy of prematurity (ROP).
Methods: This retrospective cohort study included infants born at 22 to 27 weeks' gestation between 2008 and 2018 who were admitted to neonatal intensive care units (NICUs). We compared mortality and morbidities between infants who received erythropoietin and those who did not.
Objectives: The management of patent ductus arteriosus (PDA) is a critical concern in premature infants, and different hospitals may have varying treatment policies, fluid management strategies, and incubator humidity. The Asian Neonatal Network Collaboration (AsianNeo) collected data on prematurity care details from hospitals across Asian countries. The aim of this study was to provide a survey of the current practices in the management of PDA in premature infants in Asian countries.
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- The Choosing Wisely campaign aims to reduce medical overactivity, focusing on pediatric care in Europe and Japan.
- An online survey was conducted with clinicians to rank 18 examples of medical overactivity based on their frequency and importance.
- Results highlighted common issues like inappropriate use of cough/cold medicines, antibiotics, and unnecessary tests, stressing the need for recommendations to address these challenges.
Article Synopsis
- Very low birth weight infants (VLBWIs) with esophageal atresia (EA) face significant risks for poor outcomes, including survival and neurodevelopmental issues.
- A study analyzed 103 VLBWIs with EA and found that 68% were discharged from the NICU, but survival rates decreased with lower birth weights and the presence of associated anomalies.
- Neurodevelopmental impairment (NDI) affected about 35% of patients at a 3-year follow-up, also increasing with lower birth weight, indicating that these infants need careful monitoring even after NICU discharge.
The International Liaison Committee on Resuscitation engages in a continuous review of new, peer-reviewed, published cardiopulmonary resuscitation and first aid science. Draft Consensus on Science With Treatment Recommendations are posted online throughout the year, and this annual summary provides more concise versions of the final Consensus on Science With Treatment Recommendations from all task forces for the year. Topics addressed by systematic reviews this year include resuscitation of cardiac arrest from drowning, extracorporeal cardiopulmonary resuscitation for adults and children, calcium during cardiac arrest, double sequential defibrillation, neuroprognostication after cardiac arrest for adults and children, maintaining normal temperature after preterm birth, heart rate monitoring methods for diagnostics in neonates, detection of exhaled carbon dioxide in neonates, family presence during resuscitation of adults, and a stepwise approach to resuscitation skills training.
View Article and Find Full Text PDFThe International Liaison Committee on Resuscitation engages in a continuous review of new, peer-reviewed, published cardiopulmonary resuscitation and first aid science. Draft Consensus on Science With Treatment Recommendations are posted online throughout the year, and this annual summary provides more concise versions of the final Consensus on Science With Treatment Recommendations from all task forces for the year. Topics addressed by systematic reviews this year include resuscitation of cardiac arrest from drowning, extracorporeal cardiopulmonary resuscitation for adults and children, calcium during cardiac arrest, double sequential defibrillation, neuroprognostication after cardiac arrest for adults and children, maintaining normal temperature after preterm birth, heart rate monitoring methods for diagnostics in neonates, detection of exhaled carbon dioxide in neonates, family presence during resuscitation of adults, and a stepwise approach to resuscitation skills training.
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