Bioavailability of Anthocyanin Cyanidin-3-Glucoside from Black Rice (Oryza sativa L.) Extract after Co-Administration with Allyl Isothiocyanate in Rats.

Black rice (BR) is beneficial for the health of animals and humans. Herein, we investigated the pharmacokinetics of cyanidin-3-glucoside (C3G), a major anthocyanin constituent of BR, in male rats. After its intravenous administration, C3G was rapidly distributed throughout the body and disappeared from the plasma.

Impact of a brief series of soccer matches on vascular conditions in youth women.

Background: Accumulative excessive physical load elevates central arterial stiffness and smooth muscular tone of peripheral vascular beds in endurance athletes. The aim of this study was to test the hypothesis that a brief series of soccer matches would increase central arterial stiffness and arterial wave reflection from the periphery in young female football players.

Methods: Fifteen subjects (17.

Cognitive Function among Young Women's Football Players in the Summer Heat.

Recently, there has been a growing focus on studies related to women's football. However, the cognitive function of female football players has not been extensively characterized. Thus, we explored how the cognitive function of female football players was altered during a series of matches in summer and examined day-to-day variations in cognitive function with regard to dehydration status.

Predicting central choroidal thickness from colour fundus photographs using deep learning.

The estimation of central choroidal thickness from colour fundus images can improve disease detection. We developed a deep learning method to estimate central choroidal thickness from colour fundus images at a single institution, using independent datasets from other institutions for validation. A total of 2,548 images from patients who underwent same-day optical coherence tomography examination and colour fundus imaging at the outpatient clinic of Jichi Medical University Hospital were retrospectively analysed.

Evaluating the indicators of a heart rate variability analysis in dogs using Poincaré plots.

Heart rate variability analyses using Poincaré plots can be useful for evaluating the autonomic nervous system function. However, the interpretation of the quantitative indicators of Poincaré plots remains controversial. Thus, few studies have verified the effectiveness of the quantitative indicators in veterinary medicine.

Estimation of center of pressure information by smartphone sensors for postural control training.

Postural control training based on physical information is a common rehabilitation training method for patients with movement disorder. This research aims to verify the feasibility of using one smartphone embedded sensors to estimate CoP (Center of Pressure) displacement to take postural control training. We tested the reliability of smartphone sensor by motion capture system based on the following two CoP calculation models: (1) one-link inverted pendulum model; (2) two-link inverted pendulum model.

Endovascular treatment for a ruptured lumbar artery aneurysm in a patient with neurofibromatosis type 1.

The present medical case report describes successful endovascular treatment via stent graft and coil packing for a ruptured lumbar artery aneurysm in a 55-year-old woman with neurofibromatosis type 1. Although less common, vasculopathy, such as an aneurysm, stenosis, rupture, and arteriovenous fistula, have been reported and can be a cause of death for patients with this disorder. However, only a few cases of a ruptured lumbar aneurysm have been reported.

Effect of experimentally induced plantar pain on trunk posture during gait.

[Purpose] Plantar pain is associated with the prevalence of low back pain. Therefore, it is reasonable to assume that some kind of physical change should be occurring in the trunk due to plantar pain. However, the physical effect of plantar pain on the trunk remains unknown.

Vancomycin Hydrochloride as a Risk Factor for Acute Kidney Injury: A Retrospective Study.

Introduction: The incidence of acute kidney injury (AKI) caused by vancomycin hydrochloride (VCM) was reported to be 5-43%. VCM-induced AKI was reported to be more likely to occur 4-17 days after initiating VCM treatment; however, it may occur earlier. The aim of this study was therefore to investigate risk factors for the development of AKI within two (AKI2days) and seven (AKI7days) days of VCM administration.

Effect of Sway Frequency on the Joint Angle and Center of Pressure in Voluntary Sway.

Voluntary sway is the periodic movement of one's body back and forth. The study aimed to clarify the effects of sway frequency on center of pressure and joint angle during voluntary sway. We measured 10 unrestricted voluntary sway conditions with different frequencies and natural pace conditions.

Peak vertical ground force of hand-knee crawling in human adults.

[Purpose] Fall risk is immanent in humans because they are bipedal. Bipedalism has transited from quadrupedalism in both evolutional and developmental contexts. Past studies have measured the peak vertical ground force of forelimbs and hindlimbs in quadrupedalism; and revealed that load dominancy shifted from forelimbs to hindlimbs during evolution.

Weak Inhibitory Effects of Anthocyanins on Human Aldehyde Oxidase Activity: An In Vitro Study.

Aldehyde oxidase (AO) plays an important role in the metabolism of antitumor and antiviral drugs, including methotrexate, favipiravir, and acyclovir. The consumption of blueberry fruits or their extracts, which contain large amounts of anthocyanins, has recently increased. The intake of large amounts of anthocyanins occurs through the frequent consumption of blueberries or their functional foods, which may result in unwanted interactions between anthocyanins and medicinal drugs.

Awareness of Infectious Disease Screening During Early Pregnancy and Knowledge About its Vertical Transmission in Japan: A Report from the Pregnant Women Health Initiative.

Objectives: We aimed to clarify the accuracy of pregnant women's knowledge and understanding regarding infectious disease screening in early pregnancy and clarify the roles that should be played by health care providers in promoting the health of pregnant women and their children.

Methods: A cross-sectional questionnaire survey was conducted in 25 hospitals across Japan from May 2018 to September 2019. We compared the agreement rates regarding screening results for hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis, human T-cell leukemia virus-1 (HTLV-1), and cervical cytology in the medical records and understanding of their results by pregnant women.

Influence of mutation in the regulatory domain of α-isopropylmalate synthase from Saccharomyces cerevisiae on its activity and feedback inhibition.

Isoamyl alcohol (i-AmOH) is produced from α-ketoisocaproate in the l-leucine biosynthetic pathway in yeast and controlled by the negative feedback regulation of α-isopropylmalate synthase (IPMS), which senses the accumulation of l-leucine. It is known that i-AmOH production increases when mutations in the regulatory domain reduce the susceptibility to feedback inhibition. However, the impact of mutations in this domain on the IPMS activity has not been examined.

Surgical skill and oncological outcome of laparoscopic radical hysterectomy: JGOG1081s-A1, an ancillary analysis of the Japanese Gynecologic Oncology Group Study JGOG1081.

Objectives: We investigated whether surgical skill and procedure were related to oncological outcomes in cervical cancer patients who underwent Laparoscopic Radical Hysterectomy (LRH).

Methods: We previously assessed data of LRH from 251 patients with FIGO stage (2009) IA2, IB1and IIA1 cervical cancer collected for JGOG 1081s study. 1) The JGOG 1081s cohort study was re-examined to refine the surgical details and extend the follow-up period as chart review.

Heteroepitaxial Growth of a TaN Thin Film with Clear Anisotropic Optical Properties.

TaN is a promising semiconductor photocatalyst which can generate H gas from water under visible light illumination. It is expected that TaN exhibits a strong anisotropy in its physical properties stemming from its highly anisotropic crystal structure. However, such anisotropic properties have not been verified experimentally due to the difficulty in synthesizing a large single crystal.

Total Anthocyanin Content, Total Phenolic Content, and Antioxidant Activity of Various Blueberry Cultivars Grown in Togane, Chiba Prefecture, Japan.

More than fifty cultivated varieties of blueberries are grown under the same processing conditions on the farm at Chiba Prefectural Agricultural College in Japan. The fruits from 51 blueberry cultivars, including 16 rabbiteye (RE) cultivars (Vaccinium ashei Reade) and 35 highbush (HB) cultivars (Vaccinium corybosum L.), were evaluated for total anthocyanin contents, phenolic contents, and their contribution to antioxidant activity among cultivars.