Three dimensional analysis of chest wall motion during breathing in healthy individuals and patients with scoliosis using an ultrasonography-based system.

Unlabelled: The mechanical inefficiency during respiration in scoliosis remains unclear.

Aim: To study the three-dimensional motion of the chest wall during deep breathing in healthy and scoliotic individuals.

Materials & Methods: Three-dimensional chest wall motion during breathing was studied in 17 scoliotic patients (right thoracic curvature) and 9 healthy individuals.

Prediction of curve progression in idiopathic scoliosis from gene polymorphic analysis.

Three hundred and four girls with adolescent idiopathic scoliosis were investigated to determine if DNA polymorphisms in the vitamin D receptor (VDR), estrogen receptor (BR), and CYP17 gene were related to curve progression of idiopathic scoliosis. The results suggested that XbaJ site polymorphism in the ER gene was associated with curve progression. The Cobb's curve angle with genotype XX and Xx was statistically greater than that with genotype xx.

An analysis of chest wall and diaphragm motions in patients with idiopathic scoliosis using dynamic breathing MRI.

Study Design: The motions of chest wall and diaphragm were measured in patients with scoliosis and healthy individuals using dynamic breathing magnetic resonance imaging.

Objectives: To investigate the motions of the chest wall and the diaphragm during deep breathing in patients with idiopathic scoliosis.

Summary Of Background Data: Despite the central role of the respiratory motions in maintaining ventilation, it is difficult to measure and describe the motions because of the limited methods available.

Association between estrogen receptor gene polymorphisms and curve severity of idiopathic scoliosis.

Study Design: Analysis of the estrogen receptor gene of girls with idiopathic scoliosis.

Objectives: To determine whether estrogen receptor gene polymorphisms correlate with curve severity of adolescent idiopathic scoliosis.

Summary Of Background Data: Studies suggest that idiopathic scoliosis is a familial condition and that curve progression is related to genetically determined factors, such as skeletal and sexual growth.