Development of a Janus tissue adhesive hemostatic patch based on hydrophobically-modified Alaska pollock gelatin.

Uncontrollable hemorrhage from trauma and open surgery leads to a high percentage of death. Even though some patch-type hemostatic materials have been used in the clinic, sufficient tissue adhesion property and the management of tissue adhesion and anti-adhesion have been the challenges. In this report, we designed Janus tissue adhesive hemostatic patch, consisting of Alaska pollock gelatin (Org-ApGltn) as a support layer and decanoyl group-modified ApGltn (C10-ApGltn) with pentaerythritol poly(ethylene glycol) ether tetrasuccinimidyl glutarate (4S-PEG) as an adhesive layer, named as the C10-ApGltn patch.

Effects of partial sleep restriction and subsequent daytime napping on prolonged exertional heat strain.

Objectives: It is considered that sleep restriction is one of the risk factors for the development of exertional heat stroke and illness. However, how sleep restriction affects exertional heat strain and the nature of the coping strategy involved in this phenomenon remain unclear.

Methods: Fourteen healthy subjects were studied on four occasions: after a night of normal sleep (NS, 7-8 h) and after a night of partial sleep restriction (PSR, 4 h), each with or without taking a daytime nap during the subsequent experimental day.

Metabolic rate prediction in young and old men by heart rate, ambient temperature, weight and body fat percentage.

Objectives: An estimation of metabolic rate (MR) is needed to determine wet-bulb globe temperature (WBGT) reference values in order to reduce heat strain in physical workers. The aim of this study was to develop MR prediction equation for younger and older men in hot working environments.

Methods: We measured the MR and heart rate (HR) of both younger and older men at ambient temperatures (Ta) of 25, 30 and 35°C while they cycled on a bicycle ergometer at a workload of 30, 45 and 60% of maximal oxygen uptake (V̇O2max).

Fan-precooling effect on heat strain while wearing protective clothing.

This study compared heat strain during walking while wearing impermeable protective suits between fan-precooling and nonprecooling conditions. Six males engaged in 60 min of walking at a moderate speed (∼2.5 km/h) in a hot environment (37 °C, 40% relative humidity).

Topographical relationship between the human lateral circumflex femral artery and saphenous nerve.

This study was performed to investigate causes of various types of topographical relationship between the lateral circumflex femoral artery (L) and the saphenous nerve (S). Femoral artery (F), deep femoral artery (P), L and S of 186 legs of 93 Japanese adult cadavers were submitted to anatomy. Further, the levels of origin of L in thigh were measured.

A morphological study on the human obturator externus muscle with reference to anomalous muscle and anomalous fasciculus originating from the obturator externus muscle.

To elucidate the essential nature of the human obturator externus muscle (OE), the gross anatomy of the anomalous muscle and anomalous fasciculus originating from this muscle as well as the posterior division of the obturator nerve (P) were examined in 73 thighs of 45 Japanese adult cadavers. The investigation of anomalous muscle and anomalous fasciculus was effected by observation of the supernumerary muscular branch and supernumerary muscular twig from the P. The anomalous muscle occurring between the adductor brevis muscle (AB) and adductor minimus muscle (AMi) (37/73 thighs; 50.

Comparison of the prevalence of ventricular and supraventricular premature beats with 24-hour Holter electrocardiography between hypertensive and normotensive shift workers in a manufacturing company.

We conducted 24-hour Holter electrocardiography (ECG) among shift workers to assess whether there were differences in the prevalence of ventricular apd supraventricular premature beats between hypertensive (HT) and normotensive (NT) workers. Among the selected 24 male shift workers, 20 were fitted with 24-hour Holter ECG monitors. Nine workers were in the HT group and 11 the NT group.