[Trial of Micro CT Scanner SKYSCAN1176 for the Imaging of the Guinea Pig Cochlea in vivo].

The usefulness of the micro CT scanner system SKYSCAN1176 was evaluated for the study of the guinea pig cochlea. Each slice of the section was 9 μm and we were able to identify each ossicles, modiolus, upper, middle, and basal turn of the cochlea. This scanner enables us to observe inner ear structure repeatedly in vivo.

Ototoxicity of acetic acid on the guinea pig cochlea.

Background: To evaluate the ototoxicity of acetic acid solutions.

Methods: Compound action potentials (CAPs) of the eighth nerve were measured in guinea pigs before and after the application of acetic acid in the middle ear cavity. The pH values of the acetic acid solutions were pH 3.

Ototoxicity of gentian violet on the guinea pig cochlea.

Purpose: Gentian violet (GV) is an antimicrobial and antifungal agent that has been used widely to treat intractable discharge in the ear. The purpose of this report is to warn clinicians about the ototoxic effect of GV in the middle ear.

Materials And Methods: GV ototoxicity was evaluated by measuring compound action potentials (CAPs) in the VIIIth nerve in adult Hartley guinea pigs.

Ototoxicity of Burow solution on the guinea pig cochlea.

Purpose Of The Study: The aim of the present study was to evaluate the ototoxicity of Burow solution.

Procedures: Compound action potentials (CAPs) of the eighth nerve were measured before and 30 minutes after the application of the Burow solution in the middle ear cavity.

Results: Use of the original Burow solution (pH 3.

Temporal bone histopathological features of a worker who received high doses of radiation in a criticality accident: a case report.

In 1999, three workers received high doses of radiation in a small Japanese plant while they were preparing fuel for an experimental reactor. This criticality accident at melting point was caused by the addition of too much uranium enriched to a relatively high level, causing a 'criticality' (a limited uncontrolled nuclear chain reaction), which continued intermittently for 20 h. The three workers concerned were hospitalized, two in a critical condition.

Chronological changes in the eighth cranial nerve compound action potential (CAP) in experimental endolymphatic hydrops: the effects of altering the polarity of click sounds.

Conclusion: Using a guinea pig model of experimental endolymphatic hydrops, click sounds of altered polarity showed different latencies and amplitudes in hydropic compared with normal cochleae. Latency changes appeared as early as 1 week after endolymphatic obstruction. This method can help diagnose endolymphatic hydrops.