Objective: The aim: Aim of study is to assess the influence of urgent reperfusion strategy on the levels of vWf, PAI-1 and sCD40L in patients with acute myocardial infarction (AMI) and concomitant diabetes mellitus type 2 (DM2).
Patients And Methods: Materials and methods: 255 patients with acute myocardial infarction took part in the study, they were divided into four groups depending on the presence of concomitant diabetes mellitus type 2 and performed treatment: I group - 83 diabetic patients who were underwent urgent reperfusion therapy; II group - 60 diabetic patients who received standard anticoagulant therapy; III group - 65 non-diabetic patients who were underwent urgent reperfusion therapy; IV group - 47 non-diabetic patients who received standard anticoagulant therapy. The levels of von Willebrand factor, PAI-1 and sCD40L were determined by enzyme-linked immunosorbent assay.