Gut microbiota as an efficacy marker of surgical treatment of obesity.

Objective: Aim: To study the impact of bariatric interventions on changes in the parameters of the intestinal microbiome.

Patients And Methods: Materials and Methods: The research method is a prospective observational cohort monocentric study. 112 patients were included in the study.

The use of botulinum toxin type a to prepare patients with large ventral hernias for laparoscopic hernioplasty: Our experience.

Objective: Aim: To study the effectiveness of BTA in a total dose of 100 IU as the preparation for patients with primary and incisional ventral hernias (VH).

Patients And Methods: Materials and Methods: The prospective study included 59 patients with large VH (defect ³10 cm). All patients received 100 IU of BTA in abdominal wall muscles 4-5 weeks before surgery from June 2017 to December 2022.

Strength comparison of different methods of closing the anterior abdominal wall defect (experimental study).

Objective: The aim of the study is to compare the mesh implantation and the strength of the mesh fixation to the anterior abdominal wall by modelling the intraperitoneal onlay mesh repair (IPOM) with and without aponeurotic defect closure.

Patients And Methods: Materials and methods: The experimental animals were randomly divided into 2 groups of 6 rabbits. In experimental group IPOM was modelled without hernia defect closure, in control group - with its suturing.