Publications by authors named "Tetiana P Ruban"
Article Synopsis
- The study examines the biocompatibility and osteoinductive properties of bioactive ceramics made from single-phase hydroxyapatite (HAP) and two-phase HAP with β-TCP, focusing on various chemical modifications.
- The results show that treatments improved the ceramics' solubility, increased porosity, and enhanced adsorption activity, leading to favorable conditions for cell adhesion and survival in culture.
- Calcium phosphate ceramics were found to stimulate important cellular processes, suggesting these HAP-based bioceramics could be effective for bone regeneration and reconstruction.
β-Catenin signaling pathway regulates cardiomyocytes proliferation and differentiation, though its involvement in metabolic regulation of cardiomyocytes remains unknown. We used one-day-old mice with cardiac-specific knockout of β-catenin and neonatal rat ventricular myocytes treated with β-catenin inhibitor to investigate the role of β-catenin metabolism regulation in perinatal cardiomyocytes. Transcriptomics of perinatal β-catenin-ablated hearts revealed a dramatic shift in the expression of genes involved in metabolic processes.
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