Severity and duration of hypoxemia during outpatient endoscopy in obese patients: a retrospective cohort study.

Purpose: We sought to quantify the severity and duration of hypoxemic events in morbidly obese patients during outpatient endoscopy procedures performed under deep sedation.

Methods: This was a retrospective cohort study using intraprocedural pulse oximetry readings from 11,595 American Society of Anesthesiologists physical status score I-III adult patients who underwent deep sedation for elective endoscopy at free standing ambulatory centres between June 2015 and June 2016. Unadjusted and risk-adjusted logistic regression analyses explored the relationship between increasing categories of body mass index (BMI) and intraoperative hypoxemia, severe hypoxemia, and prolonged hypoxemia.

General anesthesia in a patient with citrullinemia using Precedex as an adjunct to prevent delayed emergence.

Citrullinemia type I is a rare autosomal recessive genetic condition that causes reduced activity of the enzyme, argininosuccinate synthase, which is needed for proper urea metabolism. The end result is hyperammonemia which can cause life-threatening neurologic symptoms and global developmental delay. Previous case reports of the anesthetic management of patients with citrullinemia describe delayed recovery possibly related to elevated ammonia levels postoperatively or choice of intraoperative anesthetics which have included narcotics.

A prospective, randomized, placebo-controlled study evaluating the efficacy of dexmedetomidine for sedation during vascular procedures.

To examine the efficacy of dexmedetomidine (DEX) as a primary sedative during vascular procedures performed under monitored anesthesia care (MAC). A total of 55 patients were randomized in a 2:2:1 ratio to receive either DEX 1.0 microg/kg load or DEX 0.