Publications by authors named "Tessa Chaworth-Musters"

Article Synopsis
  • This study looks at maternal bradycardia (slow heart rate) following childbirth, noting that while tachyarrhythmias are common in pregnancy, there's less info on bradycardia.
  • Researchers reviewed charts of 24 patients treated for post-partum bradycardia, finding that most cases involved sinus bradycardia and symptoms like dyspnea and chest pain.
  • The condition often resolves on its own within a few days, with common underlying issues including preeclampsia and medications, and most cases only needing clinical observation.
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Background: COVID-19 pandemic has influenced health care delivery. We conducted an observational study to understand how obstetric medicine (ObM) physicians utilized home blood pressure monitoring (HBPM) to manage hypertension in pregnancy.

Methods: Pregnant participants with risk factors or diagnosis of hypertensive disorders of pregnancy (HDP) were enrolled, May 2020-December 2021, and provided with validated home blood pressure (BP) monitor.

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Article Synopsis
  • The study focused on understanding the factors that contribute to preterm birth (PTB) in women living with HIV in British Columbia, Canada, while examining the effects of combined antiretroviral therapy (cART) and other health determinants.
  • It analyzed data from 631 singleton pregnancies and found that the overall spontaneous preterm birth (sPTB) rate was 16%, with cumulative cART use linked to a reduced risk of sPTB.
  • The findings concluded that while sPTB rates among pregnant women with HIV were significantly higher than the general population, cART use did not increase the risk; instead, issues like uncontrolled viral load and substance use were more strongly associated with higher sPTB
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Introduction: Combination antiretroviral therapy (cART) can effectively prevent vertical transmission of HIV but there is potential risk of adverse maternal, foetal or infant effects. Specifically, the effect of cART use during pregnancy on mitochondrial DNA (mtDNA) content in HIV-positive (HIV+) women is unclear. We sought to characterize subclinical alterations in peripheral blood mtDNA levels in cART-treated HIV+ women during pregnancy and the postpartum period.

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Introduction: The objective of this study was to evaluate a province-wide program designed to identify HIV infection accurately and to prevent mother to child transmission among high-risk pregnant women of unknown serostatus.

Methods: Between 2000 and 2007, 347 high-risk women were identified through the Prevention of Mother to Child Transmission (PMTCT) program implemented in 27 hospitals across British Columbia. Rates of HIV transmission and details of the implementation of prophylaxis kits were assessed.

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Enterohemorrhagic and enteropathogenic Escherichia coli (EHEC and EPEC) maintain an extracellular lifestyle and use a type III secretion system to translocate effector proteins into the host cytosol. These effectors manipulate host pathways to favor bacterial replication and survival. NleA is an EHEC/EPEC- and related species-specific translocated effector protein that is essential for bacterial virulence.

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