Exploring the Experiences of Visiting Veterinary Service Providers in Indigenous Communities in Canada: Proposing Strategies to Support Pre-Clinical Preparation.

Many Indigenous communities in Canada lack access to veterinary services due to geography, affordability, and acceptability. These barriers negatively affect the health of animals, communities, and human-animal relationships. Canadian veterinary colleges offer veterinary services to Indigenous communities through fourth-year veterinary student rotations.

Supporting Positive Learning Experiences for Veterinary Students on Rotations in Remote Indigenous Communities in Canada.

Many health care programs in medicine, nursing, social work, and physiotherapy include practicum rotations near the end of students' studies. Increasingly, veterinary education programs also offer community-based rotations in underserved or remote communities. While these opportunities in veterinary medicine provide many learning benefits, they can also be stressful if the students do not feel adequately supported.

Actualizing Cultural Humility: An Exploratory Study of Veterinary Students' Participation in a Northern Community Health Rotation.

Rotations in diverse, marginalized communities may offer health care students opportunities to develop cultural humility through different clinical experiences and activities. Through the actualization of cultural humility, veterinarians may offer accessible, affordable, culturally proficient, high-quality care to all their patients with a better understanding of how cultural differences affect the animal patient's health, well-being, and care. The purpose of this study was to explore whether participation in a community rotation in remote northern Indigenous communities promotes cultural humility among final-year veterinary students.

The missing link in gravitational-wave astronomy: A summary of discoveries waiting in the decihertz range.

Since 2015 the gravitational-wave observations of LIGO and Virgo have transformed our understanding of compact-object binaries. In the years to come, ground-based gravitational-wave observatories such as LIGO, Virgo, and their successors will increase in sensitivity, discovering thousands of stellar-mass binaries. In the 2030s, the space-based will provide gravitational-wave observations of massive black holes binaries.

11 years of regular access to subsidized veterinary services is associated with improved dog health and welfare in remote northern communities.

Access to veterinary services can have positive impacts on animal health and welfare, and on human mental and physical health and well-being; however, many communities worldwide lack access to such services. At their request, the 5 communities of the Sahtu Settlement Area, Northwest Territories, Canada, have received annual access to preventive veterinary services through the University of Calgary's Northern Community Health Rotation since 2008. To determine the reach of the program, we conducted a dog census in 2017.

Experimental and computational studies of the mechanism of iron-catalysed C-H activation/functionalisation with allyl electrophiles.

Synthetic methods that utilise iron to facilitate C-H bond activation to yield new C-C and C-heteroatom bonds continue to attract significant interest. However, the development of these systems is still hampered by a limited molecular-level understanding of the key iron intermediates and reaction pathways that enable selective product formation. While recent studies have established the mechanism for iron-catalysed C-H arylation from aryl-nucleophiles, the underlying mechanistic pathway of iron-catalysed C-H activation/functionalisation systems which utilise electrophiles to establish C-C and C-heteroatom bonds has not been determined.

What Do Veterinary Students Value about Service Learning? Insights from Subsidized Clinics in an Urban Environment.

To promote accessible veterinary care in the community and to help students refine their communication skills, the University of Calgary, Faculty of Veterinary Medicine (UCVM) partnered with the Calgary Urban Project Society (CUPS), a human services organization, to develop the UCVM-CUPS Pet Health Clinics. These clinics are a service-learning experience where third-year students provide services to those facing barriers to veterinary care in Calgary, Alberta. The clinics are offered at CUPS for 6 weeks at 1 day per week.

Indigenous community perspectives on dogs in Northern Canada after 10 years of veterinary services indicates improved animal and human welfare.

Access to veterinary services in marginalized communities has important implications for people and animals around the world. Subsidized veterinary services are occasionally provided, however, they are seldom evaluated for their value to stakeholders and overall animal health. In 2017, we evaluated a decade-long veterinary program in four remote communities in the Sahtu Settlement Area of the Northwest Territories, Canada to understand if there were changes in dog husbandry and community perceptions of, and experiences with, dogs since an initial assessment at the beginning of the program in 2008.

The Exceptional Diversity of Homoleptic Uranium-Methyl Complexes.

Homoleptic σ-bonded uranium-alkyl complexes have been a synthetic target since the Manhattan Project. The current study describes the synthesis and characterization of several unprecedented uranium-methyl complexes. Amongst these complexes, the first example of a homoleptic uranium-alkyl dimer, [Li(THF) ] [U (CH ) ], as well as a seven-coordinate uranium-methyl monomer, {Li(OEt )Li(OEt ) UMe Li} were both crystallographically identified.

Identification and Reactivity of Cyclometalated Iron(II) Intermediates in Triazole-Directed Iron-Catalyzed C-H Activation.

While iron-catalyzed C-H activation offers an attractive reaction methodology for organic transformations, the lack of molecular-level insight into the in situ formed and reactive iron species impedes continued reaction development. Herein, freeze-trapped Fe Mössbauer spectroscopy and single-crystal X-ray crystallography combined with reactivity studies are employed to define the key cyclometalated iron species active in triazole-assisted iron-catalyzed C-H activation. These studies provide the first direct experimental definition of an activated intermediate, which has been identified as the low-spin iron(II) complex [(sub-A)(dppbz)(THF)Fe](μ-MgX), where sub-A is a deprotonated benzamide substrate.

Multinuclear iron-phenyl species in reactions of simple iron salts with PhMgBr: identification of Fe(μ-Ph)(THF) as a key reactive species for cross-coupling catalysis.

The first direct syntheses, structural characterizations, and reactivity studies of iron-phenyl species formed upon reaction of Fe(acac) and PhMgBr in THF are presented. Reaction of Fe(acac) with 4 equiv. PhMgBr in THF leads to the formation of [FePh(μ-Ph)] at -80 °C, which can be stabilized through the addition of -methylpyrrolidone.

Are we adequately evaluating subsidized veterinary services? A scoping review.

The World Health Organization (WHO) and the World Organization for Animal Health (OIE) both recognize the importance of veterinary services in controlling zoonotic diseases, in preventing human injury, and in protecting the welfare of non-human animals. Furthermore, both organizations recommend regular evaluations of veterinary programs. Accordingly, we conducted a scoping review to collate the available peer-reviewed evaluations of subsidized small animal veterinary services in terms of the effects on animal and public health.

Backbone Dehydrogenation in Pyrrole-Based Pincer Ligands.

Treatment of both [CoCl( PNP)] and [NiCl( PNP)] ( PNP = anion of 2,5-bis((di- tert-butylphosphino)methyl)pyrrole) with one equivalent of benzoquinone affords the corresponding chloride complexes containing a dehydrogenated PNP ligand, dPNP ( dPNP = anion of 2,5-bis((di- tert-butylphosphino)methylene)-2,5-dihydropyrrole). Dehydrogenation of PNP to dPNP results in minimal change to steric profile of the ligand but has important consequences for the resulting redox potentials of the metal complexes, resulting in the ability to isolate both [CoH( dPNP)] and [CoEt( dPNP)], which are more challenging (hydride) or not possible (ethyl) to prepare with the parent PNP ligand. Electrochemical measurements with both the Co and Ni dPNP species demonstrate a substantial shift in redox potentials for both the M(II/III) and M(II/I) couples.

Ice road vets: Perspectives on the role of veterinarians in northern community health.

We reflect on our experiences providing veterinary services in 5 remote communities of the Sahtu Settlement Area in the Northwest Territories in February 2017. The evolving role of dogs and the social determinants of health that influence dog health in the communities are explored, including biology, physical environment, behavior, dog and human social factors, and access to veterinary care. The importance of continued exposure of veterinary professionals to different cultural perspectives in order to provide services that are culturally appropriate and effective is highlighted.

The N-Methylpyrrolidone (NMP) Effect in Iron-Catalyzed Cross-Coupling with Simple Ferric Salts and MeMgBr.

The use of N-methylpyrrolidone (NMP) as a co-solvent in ferric salt catalyzed cross-coupling reactions is crucial for achieving the highly selective, preparative scale formation of cross-coupled product in reactions utilizing alkyl Grignard reagents. Despite the critical importance of NMP, the molecular level effect of NMP on in situ formed and reactive iron species that enables effective catalysis remains undefined. Herein, we report the isolation and characterization of a novel trimethyliron(II) ferrate species, [Mg(NMP) ][FeMe ] (1), which forms as the major iron species in situ in reactions of Fe(acac) and MeMgBr under catalytically relevant conditions where NMP is employed as a co-solvent.

Substituent Effects on the Coordination Chemistry of Metal-Binding Pharmacophores.

A combination of XAS, UV-vis, NMR, and EPR was used to examine the binding of a series of α-hydroxythiones to CoCA. All three appear to bind preferentially in their neutral, protonated forms. Two of the three clearly bind in a monodentate fashion, through the thione sulfur alone.

Magnetic circular dichroism and density functional theory studies of electronic structure and bonding in cobalt(ii)-N-heterocyclic carbene complexes.

The combination of simple cobalt salts and N-heterocyclic carbene (NHC) ligands has been highly effective in C-H functionalization, hydroarylation and cross-coupling catalysis, though displaying a strong dependence on the identity of the NHC ligand. In addition, reactions effective with NHC ligands are often ineffective with phosphine ligands, further motivating the evaluation of the fundamental electronic structure and bonding differences in well-defined distorted tetrahedral Co(ii) complexes. Magnetic circular dichroism (MCD) studies indicate that Co(ii)-bisphosphines have larger ligand fields than Co(ii)-NHC complexes.

Magnetic circular dichroism studies of iron(ii) binding to human calprotectin.

Calprotectin (CP) is an abundant metal-chelating protein involved in host defense, and the ability of human CP to bind Fe(ii) in a calcium-dependent manner was recently discovered. In the present study, near-infrared magnetic circular dichroism spectroscopy is employed to investigate the nature of Fe(ii) coordination at the two transition-metal-binding sites of CP that are a HisAsp motif (site 1) and a His motif (site 2). Upon the addition of sub-stoichiometric Fe(ii), a six-coordinate (6C) Fe(ii) center associated with site 2 is preferentially formed in the presence of excess Ca(ii).

Crystal structure of a third polymorph of tris-(acetyl-acetonato-κ(2) O,O')iron(III).

In the structure of the title complex, [Fe(C5H7O2)3] or Fe(acac)3, the asymmetric unit contains one mol-ecule in a general position. The coordination sphere of the Fe(III) atom is that of a slightly distorted octahedron. The crystal under investigation was a two-component pseudo-merohedral twin in the monoclinic system with a β angle close to 90°.

Cosmology and Fundamental Physics with the Euclid Satellite.

Euclid is a European Space Agency medium-class mission selected for launch in 2019 within the Cosmic Vision 2015-2025 program. The main goal of Euclid is to understand the origin of the accelerated expansion of the universe. Euclid will explore the expansion history of the universe and the evolution of cosmic structures by measuring shapes and red-shifts of galaxies as well as the distribution of clusters of galaxies over a large fraction of the sky.