Publications by authors named "Teshome Geremew"
Article Synopsis
- The study synthesized nine heterocyclic analogs of curcumin, achieving high yields and faster reaction times using ultrasonic irradiation, and assessed their antibacterial and anti-diabetic properties.
- Compound 11 showed strong antibacterial activity, with better binding affinities to bacterial proteins than amoxicillin, and compounds 11 and 16 demonstrated superior inhibition of the α-amylase enzyme compared to the standard drug acarbose.
- Compound 8 exhibited promising antioxidant properties, effectively scavenging free radicals, indicating its potential therapeutic benefits alongside the antibacterial and anti-diabetic findings.
Introduction: Antibiotics are commonly used for the treatment and prevention of bacterial infections. The potency of antibiotics can be affected by factors such as temperature, light, moisture, and storage conditions. Inappropriate storage and transportation of antibiotics may lead to loss of potency earlier than the expiry date.
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