Impact of Isoniazid Preventive Therapy on Tuberculosis Incidence and Predictors of Tuberculosis Among People Living With HIV/AIDS at Debre Tabor General Hospital, Northwest Ethiopia.

The World Health Organization (WHO) recommended isoniazid preventive therapy (IPT) to decrease the effects of tuberculosis (TB) on human immunodeficiency virus (HIV) patients. However, not enough research has been conducted to determine the impact of IPT on TB incidence and their predictors. Therefore, the goal of this study was to evaluate how IPT affects the incidence of TB and identify factors that are predictive of TB among HIV/AIDS patients.

Evaluation of anti-nociceptive and anti-inflammatory activities of solvent fraction of the roots of Mesfin (Asteraceae) in mice model.

Objective: The present study was aimed at investigating the antinociceptive and anti-inflammatory activities of the solvent fractions of the roots of  Mesfin in rodent models of pain and inflammation.

Methods: Successive maceration was used as a method of extraction using solvents of increasing polarity: methanol and water. Ethyl acetate, chloroform and distilled water were used as solvents of the fraction process.

Appropriate seed source and rate enhanced the productivity of bread wheat varieties under irrigated conditions in North Mecha, Amhara region, Ethiopia.

Bread wheat is a strategic cereal crop produced ndederunder both irrigation and main rainy season in the Amhara region, Ethiopia. However, its productivity is low due to unreliable seed sources, inappropriate seed rate, and unavailability of adaptable improved varieties for a wide range of agro-ecologies. Therefore, an experiment aimed at evaluating the influence of seed sources, rates, and varieties on yield and yield-related traits under irrigated conditions was conducted during 2021 at North Mecha, Amhara region, Ethiopia, to provide information and knowledge for bread wheat researchers and producers.

Training and Active Case Detection to Prevent Leprosy: Effect on Knowledge, Attitude and Skills of Health Workers on Early Diagnosis of Leprosy in a Leprosy Hotspot District in Ethiopia.

Background: Despite all of the efforts, leprosy continues to affect hundreds of thousands of people every year, including children, showing the ongoing transmission of the disease within the population. The transmission of leprosy can be interrupted through an integrated approach that includes active case-finding, contact tracing and capacity building of health workers.

Methods: A cross-sectional study design was used to assess the knowledge, attitudes and skills of health workers in the screening and diagnosis of leprosy.

Evaluation of antibiotic utilization pattern in the treatment of acute diarrheal diseases at Debre Tabor comprehensive specialized hospital, Debre Tabor, Ethiopia: A retrospective cross-sectional study.

Background: In clinical settings all across the world, including Ethiopia, the irrational use of antibiotics to treat acute diarrhea is common. The main causes of resistance are antibiotic abuse, misuse, and underuse, and among infectious diseases, antibiotic overuse is pervasive in diarrheal infections around the world. As a result, the primary goal of this study was to evaluate antibiotic use patterns for the treatment of acute diarrheal diseases at Debre Tabor Comprehensive Specialized Hospital in North-West Ethiopia.

antidiarrheal activity of the crude extract and solvent fractions of (Rhamnaceae) leaves.

Background: Even though numerous conventional anti-diarrheal agents are available, the inherent toxicities of the drugs urge the search for alternative drugs that are safe and effective.

Objective: To evaluate the anti-diarrheal activity of crude extract and solvent fractions of leaves.

Materials And Methods: The were macerated using absolute methanol and then fractionated using solvents of different polarity indexes.

A Systematic Review of Ethnobotanical, Phytochemical, and Ethnopharmacological Studies of (Stinging Nettle).

The Urticaceae family contains 54 genera and more than 2000 species that can be found in tropical, subtropical, and temperate climates all over the world. This family includes the largest genus in the world, , which is also known as stinging nettle. Stinging hairs are present on the lower surface of the leaves and beneath the stems of , also known as the stinging nettle, herbal nettle that is dioecious, upright, and unbranched.

Hypertension self-care practice and its associated factors in Bale Zone, Southeast Ethiopia: A multi-center cross-sectional study.

Background: Hypertension is a serious threat to public health globally owing to its high prevalence and related complications. It is the main risk factor for cardiovascular disease, kidney disease, eye problems, and death. Self-care practices have been emphasized as a major element in reducing and preventing complications from hypertension.

Drug-drug interactions among hospitalized elderly in patients at medical wards of Northwest Ethiopia's Comprehensive Specialized Hospitals: A multicenter observational study.

Objective: Drug-drug interactions are of major concern due to links to untoward drug effects, hospitalizations, and serious health impacts. Elderly patients are more predisposed to drug interactions than younger patients. The present study aimed to find out the prevalence of drug-drug interactions at North West Ethiopian compressive specialized hospitals' Internal Medicine wards.

Review of Ethnobotanical and Ethnopharmacological Evidence of Some Ethiopian Medicinal Plants Traditionally Used for Peptic Ulcer Disease Treatment.

A peptic ulcer is described as the rupture of the mucosal integrity of the stomach, the duodenum, and, in certain cases, the lower esophagus as a result of contact with chloridopeptic secretions. The two most common kinds of peptic ulcer disorders are referred to as "gastric ulcer" and "duodenal ulcer." The name is derived from the location of the ulceration.

Evaluation of Wound Healing Activity of 80% Methanol Root Crude Extract and Solvent Fractions of (Dill. & A. Rich.) Walp. (Menispermaceae) in Mice.

Background: The root of (Dill. and A. Rich.

Diabetic health literacy and associated factors among diabetes mellitus patients on follow up at public hospitals, Bale Zone, South East Ethiopia, 2021.

Objective: This study was aimed to assess diabetic health literacy and associated factors among adult diabetic patients in public hospitals, Bale Zone, Southeast Ethiopia.

Methods: A hospital-based cross-sectional study was conducted among 402 diabetic patients in three public hospitals and the samples were selected using simple random sampling technique. The comprehensive functional, communicative, and critical health literacy questionnaire was used to measure diabetic health literacy.

Adherence to insulin therapy and associated factors among type 1 and type 2 diabetic patients on follow up in Madda Walabu University Goba Referral Hospital, South East Ethiopia.

Background: Non-adherence to insulin therapy is a major global public health issue that has a causal relationship with increased diabetic complications that leads to further increase in the health care cost. However, adherence to insulin therapy and associated factors among diabetic mellitus (DM) patients are still not studied adequately in Ethiopia.

Objective: To assess the adherence to insulin therapy and associated factors among type 1 and type 2 diabetic patients on follow-up at Madda Walabu University-Goba Referral Hospital, South East Ethiopia.

Evaluation of antibiotic prescribing patterns among inpatients using World Health Organization indicators: A cross-sectional study.

Objective: Even though antibiotic resistance is one of the most serious threats to global public health, it is becoming more common due to inappropriate antibiotic prescribing patterns. Thus, the purpose of this study is to assess antibiotic prescribing patterns among inpatients at an Ethiopian comprehensive specialized hospital.

Methods: An institutional-based cross-sectional study was used.

Family-based intervention for prevention and self-management of disabilities due to leprosy, podoconiosis and lymphatic filariasis versus usual care in Ethiopia: study protocol for a cluster-randomised controlled trial.

Introduction: Leprosy, podoconiosis and lymphatic filariasis (LF) are three skin-related neglected tropical diseases. All three conditions can lead to temporary and permanent impairments. These impairments progressively worsen and are major determinants of stigma, discrimination and participation restrictions.

Determinants of wasting among South Sudanese 6- to 59-month-old children in Okugo refugee camp, Gambella Region, South-Western Ethiopia: Unmatched case-control study.

Introduction: Wasting among refugee children continues to be a serious public health problem particularly in conflict and in situations when people are displaced. Evidence of risk factors in the refugee context is crucial to successfully prevent malnutrition and its consequences. However, little information is known about the determinants of wasting in a refugee setting.

Bacterial profile and their antimicrobial susceptibility patterns in patients admitted at MaddaWalabu University Goba Referral Hospital, Ethiopia: a cross sectional study.

Background: Hospital acquired infections (HAIs) are one of the global concerns in resource limited settings. The aim of the study was to determine bacteria profile and their antimicrobial susceptibility patterns among patients admitted at surgical and medical wards.

Methods: A hospital based cross-sectional study was conducted from November 2016 to July 2017 in MaddaWalabu University Goba Referral Hospital.

Survival status and predictors of mortality among traumatic brain injury patients in an Ethiopian hospital: A retrospective cohort study.

Introduction: Traumatic brain injury is a major global public health problem causing substantial mortality among the adult population. Hence, this study aimed to determine the predictors of mortality among adult traumatic brain injury patients in Felegehiwot Comprehensive Specialized Hospital in Northwest Ethiopia during 2020.

Methods: A retrospective cohort study was conducted at Felegehiwot Comprehensive Specialized Hospital using anonymized patient data obtained from chart review.

Dietary diversity and associated factors among HIV-positive adults attending the anti-retroviral therapy clinic at Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia: a cross-sectional study.

The aim of the study was to assess dietary diversity (DD) and associated factors among human immune deficiency virus (HIV)-positive adults attending the anti-retroviral therapy (ART) clinic at Felege Hiwot Comprehensive Specialized Hospital (FHCSH) in Northwest Ethiopia. An institution-based cross-sectional study was conducted at FHCSH in 2019. A systematic random sampling technique was employed to select 352 study subjects.

Evaluation of Antidiarrheal Activity of Solvent Fractions of (Rosaceae) in Swiss Albino Mice.

Background: Ethiopia has several medicinal plants that have been used for their antidiarrheal activity. is the most commonly used medicinal plant for the management of diarrhea in Ethiopia. Thus, this study's aim is to investigate the antidiarrheal effect of solvent fractions of .

A family-based intervention for prevention and self-management of disabilities due to leprosy, podoconiosis and lymphatic filariasis in Ethiopia: A proof of concept study.

A key issue for persons with leprosy-, lymphatic filariasis- and podoconiosis-related disabilities is the life-long need to practice self-management routines. This is difficult to sustain without regular encouragement and support of others. Family-based support may be a sustainable and feasible strategy to practice self-management routines.