Publications by authors named "Tesfaye Sisay"

Objective: There is limited information about the extent of metabolic syndrome (MetS) among subjects with cardiac diseases in Ethiopia. Therefore, this study aimed to determine the prevalence and associated factors of MetS among adults with cardiac diseases.

Methods: A cross-sectional study was conducted at Hawassa University Comprehensive Specialized Hospital in southern-Ethiopia between May 2021 and August 2021.

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Background: Dyspepsia is a common gastrointestinal illness sometimes associated with Helicobacter pylori (H. pylori) infection. Screening and eradicating the bacterium reduces the risk of infection-related complications.

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Article Synopsis
  • Optimization of fertilizer use (N and P) for teff production in central Ethiopia is influenced by the type of precursor crops (cereal vs. pulse) and different Vertisols types (light vs. heavy soils).
  • Significant grain yield increases were observed with higher nitrogen application rates, with a 394% yield increase at 240 kg N/ha compared to no fertilizer.
  • Optimal fertilizer recommendations for various conditions were provided, with specific N and P application rates suggested for different precursor crops and soil types across three study districts, emphasizing economic efficiency in crop production.
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Background: Anemia is the most common hematologic abnormality associated with human immunodeficiency virus (HIV)-infected patients and affects 60% to 80% of patients in late-stage disease. It has a considerable impact on the progression of HIV to advanced stages. This study aimed at assessing the burden of anemia in adult HIV-infected patients who are on highly active antiretroviral therapy (HAART) and have follow-up at Hawassa University Comprehensive Specialized Hospital (HUCSH) Antiretroviral therapy (ART) clinic.

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Animal sourced foods, such as dairy products, are common sources of , a foodborne pathogen of increasing global concern, particularly in developing countries. In Ethiopia, most data on the prevalence of in dairy products is highly varied and limited to a specific region or district. Furthermore, there is no data available on the risk factors for contamination of cow milk and cottage cheese in Ethiopia.

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E. coli are frequently isolated food-borne pathogens from meat, milk, and their products. Moreover, there has been a significant rise in the antimicrobial resistance patterns of E.

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Objectives: An accurate exponentially fitted numerical method is developed to solve the singularly perturbed time lag problem. The solution to the problem exhibits a boundary layer as the perturbation parameter approaches zero. A priori bounds and properties of the continuous solution are discussed.

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Background: Tuberculosis is commonly detected late or not at all in HIV-positive people. Rapid and sensitive molecular tests like Gene X-pert have recently become available to replace or supplement existing conventional tests for detecting tuberculosis, and the World Health Organization (WHO) recommends that these rapid techniques be used as the initial diagnostic test for tuberculosis to avoid delays in starting appropriate treatment. The lipoarabinomannan was approved by the national ministry of health in August 2021 for the detection of active tuberculosis in specified groups.

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Introduction: Pathogenic strains cause diarrheal infection in children due to their virulence factors. A nonanalytical observational study followed by a purposive sampling technique was conducted from October 2017 to June 2018, to determine the antimicrobial susceptibility patterns and molecularly detect pathogenic strains in under-five children at Wolaita Sodo town using molecular and the Kirby-Bauer disc diffusion method.

Result: In the current investigation, out of 110 stool samples, was isolated in 68 (61.

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Introduction: are among the major causes of mortality and morbidity in under-five children in developing nations including Ethiopia.

Methods: A non-analytical observational study design followed by a purposive sampling technique was conducted from October 2017 to June 2018, to isolate and determine its associated risk factors from diarrheic children that were admitted to Christian hospital, Wolaita Sodo town. was confirmed using standard culture and biochemical analyses of the bacterium.

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Article Synopsis
  • The study investigated the polymorphism of the bovine leukocyte antigens (BoLA) gene, specifically exon 2 of the BoLA class II DRB3 gene, in various zebu cattle breeds using PCR-SBT methods on 100 animals from different breeds.
  • A total of 59 alleles were identified, with 16 being unique to the study, and analysis revealed high genetic variability among zebu breeds, comparable to other cattle breeds.
  • The research found that most zebu breeds displayed a combination of allele excess and low genetic variation, with evidence of over-dominant selection and no distinct evolutionary clades among breeds in the phylogenetic analysis.
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Considering the escalating number of scientific reports on the association between the leptin gene and diverse physiological traits and performance of cattle populations, this study was directed towards identifying SNPs in the leptin gene among five indigenous cattle breeds of Ethiopia. DNA samples were extracted from the nasal swabs of the Ethiopian indigenous cattle breeds: Arsi (n = 18), Horro (n = 20), Begait (n = 21), Boran (n = 19), and Fogera (n = 17) and the Korean Hanwoo (a representative taurine breed) (n = 20), followed by PCR amplification of exon 2 and exon 3 regions of the leptin gene and sequence analysis of the PCR products. Five SNPs, two (generating missense mutations) on exon 2 and three (generating silent mutations) on exon 3 regions, were explicated in this study.

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Background: Adequate knowledge, awareness, and adherence to diabetic self-care practices are vital tools to protect patients from risks of disease complications, developing comorbidity and mortality. Therefore, this study aimed to assess specific domains of diabetic self-care practice and associated factors among patients with type-2diabetes in Hawassa University Comprehensive Specialized Hospital, Sidama regional state.

Materials And Methods: A hospital-based cross-sectional study design was conducted on 217 patients with type 2 diabetes from January 01 to April 30, 2020.

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Introduction: , , , and are traditionally used to treat urolithiasis in Ethiopia. However, there are limited reports on toxicity studies.

Objective: This study was intended to evaluate the acute and sub-acute toxicity effects of plants.

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Left ovarian vein thrombosis is a very rare and infrequent thrombotic condition that mainly occurs in the postpartum or postoperative period. We report a case of a 25-year-old para-1 woman who presented with 2 weeks of postpartum fever and dull aching abdominal pain more on the left side. Before operation, the diagnosis was left adnexal mass secondary to questionable ovarian cyst torsion and she underwent laparotomy.

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Background: Currently, cardiovascular diseases (CVDs) are rising in the world and require great concern because the consequences are not only morbidity and mortality, but also a high economic burden. However, the pattern of CVDs in Ethiopia is not well known. Therefore, this study aimed to describe CVD and co-existing morbidities among newly registered cardiac patients in Hawassa University Comprehensive Specialized Hospital.

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is one of the most harmful pathogens responsible for foodborne outbreaks, illnesses and deaths. The aim of this study was to evaluate the effect of potentially probiotic strains against Typhimurium DT104 in mice. The compatibility test among the selected potential probiotic strains ( K132 K114 and E124) using the cross-streaking method showed the absence of antagonism.

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This study was conducted in and around Debre Zeit town to assess the field efficacy of LSD vaccine in use and overview associated disease impact. The study comprised cross-sectional and retrospective study design which employed active disease follow-up, semi-structured questionnaire survey and molecular techniques. The finding revealed that the Kenyan sheep pox vaccine strain used for the control of LSD did not confer expected protection.

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