Publications by authors named "Teruhisa Tsukamoto"
Article Synopsis
- The study investigates the fungal microbiome differences between patients with conjunctival MALT lymphoma and healthy controls using advanced metagenomic techniques.
- Researchers found significant fungal dysbiosis and a variation in microbial diversity among patients, indicating a distinct clustering based on fungal abundance.
- Lower tear mucin concentrations in MALT patients suggest a possible link to allergic reactions, highlighting the importance of early treatment when high fungal abundance is observed.
Article Synopsis
- Metagenomic analysis was evaluated for its effectiveness in identifying causal organisms of bacterial endophthalmitis in 21 treatment-naïve patients.
- Seven out of 15 culture-negative cases had pathogens detected through metagenomic analysis, suggesting its potential to uncover hidden infections.
- The study found distinct differences in bacterial diversity between groups with positive and negative culture results, highlighting metagenomics' role in precise diagnosis and inflammation assessment.
Glaucoma, a progressive and irreversible optic neuropathy, is one of the leading causes of vision impairment worldwide. Elevation of intraocular pressure (IOP) due to transforming growth factor-β (TGF-β)-induced dysfunction of the trabecular meshwork is a risk factor for glaucoma, but the underlying molecular mechanisms remain elusive. Here, we show that Src kinase is involved in TGF-β-induced IOP elevation.
View Article and Find Full Text PDFBackground: Acne vulgaris is a chronic inflammatory disease involving colonization of Propionibacterium acnes (P. acnes), activation of neutrophils and lymphocytes. Circumstantial evidence suggests that antigen-independent and -dependent immune responses against P.
View Article and Find Full Text PDFEvaluation of toxicity due to vital stains in isolated rat retinas.
Acta Ophthalmol Scand
April 2004
Purpose: We investigated whether artificial aqueous humours are adequate incubation media compared with artificial cerebrospinal fluid (aCSF), and evaluated the retinal toxicity of two vital stains--trypan blue (TB) and indocyanine green (ICG)--and triamcinolone acetonide (TA) using isolated rat retinas incubated in artificial aqueous humours.
Methods: In experiment 1, retinal segments were isolated and incubated in aCSF, BSS plus, Opeguard Neo Kit, or phosphate-buffered saline (PBS). In experiment 2, retinal tissues were exposed to one of the agents and incubated in BSS plus.