Geiger-mode avalanche photodiode ladar receiver performance characteristics and detection statistics.

The performance of single and multielement Geiger-mode avalanche photodiode (GM-APD) devices are investigated as a function of the detector's reset or dead time. The theoretical results, developed herein, capture the effects of both quantum fluctuations and speckle noise and are shown to agree with Monte Carlo simulation measurements. First, a theory for the mean response or count rate to an arbitrary input flux is developed.

AAOMP case challenge: a solitary gingival nodule.

A 38-year-old Hispanic female presented for evaluation of a gingival nodule of eight months duration. The nodule, which was slightly painful to palpation, had increased in size over time. The patient denied any history of trauma to the area.

Pharmacokinetic and pharmacodynamic profile following oral administration of the phosphodiesterase (PDE)4 inhibitor V11294A in healthy volunteers.

Aims: To assess the pharmacokinetic and pharmacodynamic profile of the novel PDE4 inhibitor V11294A (3-(3-cyclopentyloxy-4-methoxybenzyl)-6-ethylamino-8-isopropyl-3H purine hydrochloride) in healthy male volunteers.

Methods: This was a double-blind, single dose, randomized crossover study in eight healthy volunteers who received a single oral, fasting dose of V11294A (300 mg) or placebo. Blood samples were taken before and 0.