Evaluation of the impact of hematocrit and other interference on the accuracy of hospital-based glucose meters.

Background: Most glucose meter comparisons to date have focused on performance specifications likely to impact subcutaneous dosing of insulin. We evaluated four hospital-based glucose meter technologies for accuracy, precision, and analytical interferences likely to be encountered in critically ill patients, with the goal of identifying and discriminating glucose meter performance specifications likely to impact intensive intravenous insulin dosing.

Methods: Precision, both within-run and day-to-day, was evaluated on all four glucose meters.