Comparative study on chromatin loop callers using Hi-C data reveals their effectiveness.

Background: Chromosome is one of the most fundamental part of cell biology where DNA holds the hierarchical information. DNA compacts its size by forming loops, and these regions house various protein particles, including CTCF, SMC3, H3 histone. Numerous sequencing methods, such as Hi-C, ChIP-seq, and Micro-C, have been developed to investigate these properties.

Predicting Change in Posttraumatic Distress Through Change in Coping Self-Efficacy After Using the My Trauma Recovery eHealth Intervention: Laboratory Investigation.

Background: Technology offers a unique platform for delivering trauma interventions (ie, eHealth) to support trauma-exposed populations. It is important to evaluate mechanisms of therapeutic change in reducing posttraumatic distress in eHealth for trauma survivors.

Objective: This study evaluated a proactive, scalable, and individually responsive eHealth intervention for trauma survivors called My Trauma Recovery.

The Extreme Value Machine.

It is often desirable to be able to recognize when inputs to a recognition function learned in a supervised manner correspond to classes unseen at training time. With this ability, new class labels could be assigned to these inputs by a human operator, allowing them to be incorporated into the recognition function-ideally under an efficient incremental update mechanism. While good algorithms that assume inputs from a fixed set of classes exist, e.

Probability Models for Open Set Recognition.

Real-world tasks in computer vision often touch upon open set recognition: multi-class recognition with incomplete knowledge of the world and many unknown inputs. Recent work on this problem has proposed a model incorporating an open space risk term to account for the space beyond the reasonable support of known classes. This paper extends the general idea of open space risk limiting classification to accommodate non-linear classifiers in a multiclass setting.

Toward open set recognition.

To date, almost all experimental evaluations of machine learning-based recognition algorithms in computer vision have taken the form of "closed set" recognition, whereby all testing classes are known at training time. A more realistic scenario for vision applications is "open set" recognition, where incomplete knowledge of the world is present at training time, and unknown classes can be submitted to an algorithm during testing. This paper explores the nature of open set recognition and formalizes its definition as a constrained minimization problem.

Meta-Recognition: The Theory and Practice of Recognition Score Analysis.

In this paper, we define meta-recognition, a performance prediction method for recognition algorithms, and examine the theoretical basis for its postrecognition score analysis form through the use of the statistical extreme value theory (EVT). The ability to predict the performance of a recognition system based on its outputs for each match instance is desirable for a number of important reasons, including automatic threshold selection for determining matches and nonmatches, and automatic algorithm selection or weighting for multi-algorithm fusion. The emerging body of literature on postrecognition score analysis has been largely constrained to biometrics, where the analysis has been shown to successfully complement or replace image quality metrics as a predictor.

A novel approach to medical image compression.

As medical/biological imaging facilities move towards complete film-less imaging, compression plays a key role. Although lossy compression techniques yield high compression rates, the medical community has been reluctant to adopt these methods, largely for legal reasons, and has instead relied on lossless compression techniques that yield low compression rates. The true goal is to maximise compression while maintaining clinical relevance and balancing legal risk.