Analysis of craniofacial and extremity growth in patients with growth hormone deficiency during growth hormone therapy.

Background/aims: There are many controversies regarding side effects on craniofacial and extremity growth due to growth hormone (GH) treatment. Our aim was to estimate GH action on craniofacial development and extremity growth in GH-deficient patients.

Methods: Twenty patients with GH deficiency with a chronological age ranging from 4.