Publications by authors named "Tereza Cristina Esteves"
Beyond Clinical Trials: Understanding Neurotrophic Tropomyosin Receptor Kinase Inhibitor Challenges and Efficacy in Real-World Pediatric Oncology.
Carolina Sgarioni Camargo Vince Maria Sol Brassesco Bruna Minniti Mançano Lauro Jose Gregianin Edna Kakitani Carbone Tereza Cristina Esteves
JCO Precis Oncol
May 2024
Article Synopsis
- - The study focused on treatment experiences for kids with NTRK-fused tumors, looking at access to care, how they responded to treatment, side effects, and overall health outcomes.
- - Researchers reviewed data from 17 pediatric cases treated with larotrectinib, identifying six NTRK fusion subtypes and noting that 11 of 14 patients had positive tumor responses, with various levels of adverse effects reported.
- - The findings suggest that larotrectinib is effective for treating these tumors in children, but challenges still exist in ensuring consistent access to treatment, particularly in countries with limited resources like Brazil.
Metanephric adenoma is an extremely rare tumor of the kidney. The clinical and anatomic characteristics are not yet well defined, but it is currently considered to be a benign tumor with a good prognosis, although recently two metastatic cases have been reported. Around 50% of cases are incidental findings, and symptoms include polycythemia, abdominal pain, hematuria and palpable mass.
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