[Preoperative stress testing in patients prior to vascular surgery].

Myocardial infarction is the leading cause of mortality during peripheral artery surgery. The review summarizes the data on cardiac event risk stratification in angiosurgical patients by preoperative stress testing. The prognostic value of positive and negative results is described.

Hemodynamic arterial changes in heart failure: a proposed new paradigm of "heart and vessels failure".

Background: Although heart failure (HF) is one of the most common conditions affecting the heart, little attention has been placed on the role of arteries in contributing to the progression of this disease. We sought to determine the hemodynamic change of arteries in HF patients subdivided according to left ventricular ejection fraction. The major goal was to establish the active compensatory role of arteries in HF.

[Clinical efficacy of reconstructive operations on the third (V3) segment of the vertebral artery].

Presented herein are the results of a prospective cohort study of clinical efficacy of medicamentous treatment and operations of shunting to the third segment (V3) of the vertebral artery in patients with vertebrobasilar insufficiency (VBI). The study included a total of 60 patients with pronounced clinical manifestations of VBI and concomitant lesions of the V1 and V2 segments of the vertebral arteries. The patients were found to have no significant involvement of the carotid bifurcation.

Treatment of vertebrobasilar insufficiency due to stenosis and aneurysm of the vertebral artery.

A dissecting aneurysm of the vertebral artery in the extracranial portion is a rare pathology. It may either have a symptom-free course or induce a clinical picture of vertebrobasilar insufficiency. To the main methods of surgical treatment belong endovascular techniques and resection of an aneurysm with shunting of the V3 segment of the vertebral artery.

[Perioperative use of statins in vascular surgery].

The review is dedicated to studying the effect of perioperative use of statins while performing vascular operations, examining possible aftermaths of statins discontinuation in the perioperative period and discussing safety of perioperative use of statins. Cardiovascular complications constitute the most common cause of perioperative mortality while performing major noncardiac operations. Clinical studies demonstrated a favourable effect of statins on the cardiovascular complications rate in the perioperative period, therefore use of statins for prevention of cardiovascular diseases seems substantiated appropriate.

[Endovascular treatment of a female patient with resistant arterial hypertension secondary to a renal artery aneurysm].

Described herein is a successful therapeutic outcome in a female patient presenting with resistant arterial hypertension secondary to a gigantic intraorganic aneurysm of the right renal artery. Treatment consisted of intravascular prosthetic repair of the parenchymatous portion of the renal artery, eventually making itpossible to entirely bypass the aneurysmatic sac and to restore the lumen of the renal artery, followed by normalization of arterial pressure.

[Surgical treatment of the patients with fibromuscular dysplasia of internal carotid arteries].

The results of surgical treatment of 78 patients with fibromuscular dysplasia (FMD) of internal carotid artery (ICA) were described in the article. FMD ICA was combined with atherosclerosis of carotid artery at 68 (87,2%) patients and with pathological kinking of ICA at 64 (82%) patients. We provide information about frequency of systemic inflammation response syndrome at FMD ICA, and necessity of its treatment for improvement of surgical outcomes in these patients.

[Surgical management of patients with occlusion of the internal carotid artery].

The work was aimed at determining appropriate surgical policy in patients presenting with atherosclerotic occlusion of the internal carotid artery (ICA), who had endured ischaemic carotid stroke on the side of the occluded ICA. The study was based on the findings obtained in a comprehensive examination and surgical management of 140 patients. All the 140 patients at the first stage were subjected to surgical resection of the ICA with autovenous plasty of the external carotid artery (ECA).

[Age and the vascular reaction to injury].

Our own results and the literature dates analysis showed that spontaneous endothelial cells injury in aging, and the hypertension, hypercholesterinemia, immune disorders, that was induced in experiment aggravating the process of the development of atherosclerosis.

[Role of immune complexes in the pathogenesis of atherosclerosis: age-related aspect].

The experiments on 40 young and old rabbits which were given exogenous immune complexes (IC) for a month were made to study the changes in the blood levels of circulating IC (CIC), cholesterol and lipoproteins and their relation to the degree of atherosclerotic lesions to the vessels. The old animals that had low levels of minor CIC and insignificant transient increases in blood lipids were demonstrated to develop the same vascular atherosclerotic lesions as did the young animals that had higher levels of CIC and lipids. Some old animals retained a high immunological responsiveness (high CIC levels), which was accompanied by high incidence rates and extent of aortic lipid lesions.