Publications by authors named "Teresa Trujillo-Soto"
Development and Validation of a Highly Sensitive Multiplex Immunoassay for SARS-CoV-2 Humoral Response Monitorization: A Study of the Antibody Response in COVID-19 Patients with Different Clinical Profiles during the First and Second Waves in Cadiz, Spain.
Microorganisms
December 2023
Article Synopsis
- The COVID-19 pandemic continues to challenge healthcare systems with emerging waves, necessitating new preventive tools and therapies.
- A novel immunoassay using Bio-Plex technology has been developed to simultaneously detect multiple IgG antibodies against different SARS-CoV-2 antigens, showcasing high sensitivity and specificity.
- This multiplex immunoassay serves as a robust tool for monitoring humoral immunity and can aid in epidemiological surveillance, particularly in analyzing antibody responses among unvaccinated COVID-19 patients in Cadiz, Spain.
Despite the extraordinary advances achieved to beat COVID-19 disease, many questions remain unsolved, including the mechanisms of action of SARS-CoV-2 and which factors determine why individuals respond so differently to the viral infection. Herein, we performed an analysis to identify host microRNA targeting , , and/or RAB14, all genes known to participate in viral entry and replication. Next, the levels of six microRNA candidates previously linked to viral and respiratory-related pathologies were measured in the serum of COVID-19-negative controls (n = 16), IgG-positive COVID-19 asymptomatic individuals (n = 16), and critical COVID-19 patients (n = 17).
View Article and Find Full Text PDFHuman immunodeficiency virus (HIV) antibodies have been proposed as a measure of the size of the HIV reservoir. The aim of our study is to quantify the anti-HIV antibodies level in a cohort of people living with HIV (PLWH), stratified based on the presence of continuous undetectable HIV viral load and the co-existence of hepatitis C virus infection. A sample of 229 HIV-monoinfected (n = 114) or HIV/HCV-coinfected [either with resolved HCV infection (n = 75) or active HCV coinfection (n = 40)] patients, followed up a median of 34 (IQR 20-44) months, was studied.
View Article and Find Full Text PDFis a well-adapted zoonotic bacterium associated to cases of gastroenteritis and bacteremia with increased morbidity and mortality. In this study, three isolates of Typhimurium obtained from human clinical samples, showing colistin resistance and low-level resistance to quinolones, have been genetically characterized. We detected the co-occurrence of and on a single IncHI2 plasmid in isolates of Typhimurium obtained from Spanish children without a travel history.
View Article and Find Full Text PDFIntroduction: The epidemiology of S. aureus depends on conditions in specific populations. Few studies of S.
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