Publications by authors named "Teresa Navio"
Article Synopsis
- The study aimed to assess the prevalence of SARS-CoV-2 antibodies in patients with immune-mediated inflammatory diseases (IMID) who are receiving biologic or synthetic therapies.
- Conducted from October 2020 to May 2021, researchers evaluated 550 patients and found an overall seroprevalence rate of 16%, with higher rates in those treated with tumor necrosis factor alpha inhibitors (TNFi).
- The findings also indicated that concurrent treatment with methotrexate reduced the seroprevalence in patients taking TNFi, suggesting a complex interaction between therapies affecting immune response.
Article Synopsis
- The study aimed to assess the impact of a clinical evaluation checklist on recording variables for patients with axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA).
- After implementing the checklist, significant increases in various health metrics were observed for both patient groups, with axSpA patients showing more changes than those with PsA.
- The findings suggest that using a checklist enhances patient evaluations, highlighting the need for further efforts to improve assessments, particularly for PsA patients.
Objective: Choroidal thickness (CT) has been evaluated as a marker of systemic inflammation in ankylosing spondylitis (AS). This study evaluates the CT of AS patients before and after 6 months of biological treatment.
Methods: This longitudinal multicenter study evaluated CT in 44 AS patients.
Article Synopsis
- * The study involved 182 patients who received a combined pneumococcal vaccination protocol and evaluated their immune response through a specific assay measuring antibody functionality.
- * Results indicated that patients on the drug etanercept had a better immune response to multiple pneumococcal serotypes, with about 50% of all participants developing functional antibodies post-vaccination, especially for the prevalent serotype 3.
Objectives: The aim of this study was to examine the incidence of coronavirus disease 2019 (COVID-19) among patients with immunomediated inflammatory diseases (IMIDs) treated with biologic or targeted synthetic disease-modifying antirheumatic drugs (bDMARDs and tsDMARDs) and to evaluate the influence of either IMIDs or related therapies on the incidence and evolution of COVID-19.
Methods: This observational, cross-sectional study was conducted from January 31, 2020, to May 15, 2020. Data of 902 patients were obtained from clinical records in hospitals, primary care units, and community pharmacies.
To evaluate the response to hepatitis B virus (HBV) vaccine in patients on biological therapy. Adults with autoimmune inflammatory diseases on biological therapy such as anti-TNFα, rituximab, tocilizumab, abatacept, or anakinra were included. Hepatitis B surface antibody (anti-HBs) was measured by ELISA before and after vaccination.
View Article and Find Full Text PDFObjectives: To analyse the feasibility and changes in the collection of clinical measures after the implementation in daily practice of a checklist designed for an optimal evaluation and monitoring of patients with spondyloarthritis (SpA).
Methods: An observational prospective study was performed. The feasibility of the assessment checklist (paper/on-line format) for patients with SpA was tested (time to complete the checklist, simplicity, amenity clarity, usefulness).
Nursing clinics in rheumatology (NCRs) are organisational care models that provide care centred within the scope of a nurse's abilities. To analyse the impact of NCR in the rheumatology services, national multicenter observational prospective cohort studied 1-year follow-up, comparing patients attending rheumatology services with and without NCR. NCR was defined by the presence of: (1) office itself; (2) at least one dedicated nurse; and (3) its own appointment schedule.
View Article and Find Full Text PDFObjective: To compare the carotid intima-media thickness (IMT) assessed with automated radiofrequency-based US in RA patients treated with synthetic vs synthetic and biologic DMARDs and controls.
Methods: Ninety-four RA patients and 94 sex- and age-matched controls were prospectively recruited at seven centres. Cardiovascular (CV) risk factors and co-morbidities, RA characteristics and therapy were recorded.
Objectives: To assess the reliability of the automated radio frequency (RF)-based US measurement of carotid intima-media thickness (IMT) performed by rheumatologists and to evaluate the variability between this method and the conventional B-mode US measurement of carotid IMT in RA patients.
Methods: Twelve rheumatologists measured in two blinded rounds the IMT of both common carotid arteries (CCAs) of seven RA patients with an automated RF-based method. At each round, a cardiologist measured both CCA-IMTs of the patients using an automated B-mode method.