Patient, Family, and Center-Based Factors Associated with Attrition in Neonatal Clinical Research: A Prospective Study.

Background: Attrition, or loss to follow-up, presents a significant threat to the integrity and validity of longitudinal clinical research. Little is known about predictors of attrition in neonatal clinical research, and no prior studies have examined how families' experiences participating in research with their infants influences study compliance.

Objective: To identify novel factors that were associated with attrition over 1 year of study follow-up among preterm infants enrolled in the multicenter Prematurity and Respiratory Outcomes Program (PROP) observational study.

Developmental outcomes of children with congenital diaphragmatic hernia: a multicenter prospective study.

Purpose: To determine developmental outcomes and associated factors in patients with congenital diaphragmatic hernia (CDH) at 2 years of age.

Methods: This is a multicenter prospective study of a CDH birth cohort. Clinical and socioeconomic data were collected.