von Willebrand disease and cardiopulmonary bypass: a case report.

The anesthetic management of patients undergoing cardiac surgery on cardiopulmonary bypass can be challenging. Contact of blood with extracorporeal surfaces results in altered coagulational integrity and increased risk of bleeding. Patients with preexisting bleeding disorders are particularly vulnerable.

Anesthetic management of patients with major burn injury.

Burn injury is a leading cause of life-threatening trauma worldwide, affecting more than 450,000 Americans each year, and is associated with an average mortality rate of 0.8%. Patients with an increased risk of death from burn injuries include elderly patients and patients with large burns or inhalation injury.