Publications by authors named "Teresa Cordeiro"

Background: The COVID-19 pandeminc has had widespread impacts, but its specific effects on mental health and cognitive function in patients with cancer remain under-explored.

Recent Findings: Data from the general population has suggested that mental health problems were frequent during the pandemic, namely during the initial stage of the outbreak. For patients with cancer, a systematic review and meta-analysis of data published until January 2021 also showed elevated prevalence of depression and anxiety, and suggested that anxiety was more frequent than in health workers and healthy controls.

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Article Synopsis
  • Effective drug delivery systems require understanding both the drug properties and its interaction with delivery carriers, as shown in this study of simvastatin (SIM) in mesoporous silica MCM-41.
  • SIM was found to exist in an amorphous state with a significant fraction showing strong interactions with the silica matrix, facilitating long-term stabilization.
  • Molecular Dynamics simulations indicate that SIM molecules anchor to the inner walls of the pores, leading to slower release of anchored molecules compared to the more easily released unanchored ones.
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The aim of this study was to assess the relationship between the self-concept of children and their ability to recognize emotions in others from facial expressions. It is hypothesized that children use their self-representations to interpret depictions of emotion in others and that higher self-concepts might be associated with earlier development of emotion recognition skills. A total of 54 children aged between 5 and 11 years participated in this study.

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Aiming to evaluate how the release profile of naproxen (nap) is influenced by its physical state, molecular mobility, and distribution in the host, this pharmaceutical drug was loaded in three different mesoporous silicas differing in their architecture and surface composition. Unmodified and partially silylated MCM-41 matrices, respectively MCM-41 and MCM-41, and a biphenylene-bridged periodic mesoporous organic matrix, PMO, were synthetized and used as drug carriers, having comparable pore sizes (∼3 nm) and loading percentages (∼30% w/w). The loaded guest was investigated by attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy, powder X-ray diffraction (XRD), differential scanning calorimetry (DSC), and dielectric relaxation spectroscopy (DRS).

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The amorphization of the readily crystallizable therapeutic ingredient and food additive, menthol, was successfully achieved by inclusion of neat menthol in mesoporous silica matrixes of 3.2 and 5.9 nm size pores.

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Background: Surgical access to metastases in the retropharyngeal lymph nodes (RPLNs) could be difficult. Transoral robotic surgery (TORS) can be utilized to access RPLNs. The purpose of this study was to describe a TORS approach to RPLN dissection.

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