Understanding hydrodynamic wear in self-similar superhydrophobic coatings subjected to rapid droplet impacts.

Superhydrophobic materials rely on both chemical apolarity and surface roughness to achieve the high contact angles and the low roll-off angles that lead to self-cleaning and antibacterial properties. Current superhydrophobic coatings tend to be delicate and lose their properties easily when subjected to droplet impact. Such impact deteriorates these coatings through hydrodynamic wear; changing structure, eroding hydrophobic chemistry, and quickly leading to full wet out of the substrate.

Modeling the Downstream Processing of Monoclonal Antibodies Reveals Cost Advantages for Continuous Methods for a Broad Range of Manufacturing Scales.

The biopharmaceutical industry is evolving in response to changing market conditions, including increasing competition and growing pressures to reduce costs. Single-use (SU) technologies and continuous bioprocessing have attracted attention as potential facilitators of cost-optimized manufacturing for monoclonal antibodies. While disposable bioprocessing has been adopted at many scales of manufacturing, continuous bioprocessing has yet to reach the same level of implementation.