Publications by authors named "Terance Gi-Wai Tsang"
Article Synopsis
- - Severe fever with thrombocytopenia syndrome virus (SFTSV) is a dangerous tick-borne virus with high mortality rates and limited treatment options.
- - Researchers screened FDA-approved drugs and found five compounds, including hexachlorophene, capable of inhibiting SFTSV replication, with hexachlorophene being the most effective.
- - Hexachlorophene works by stopping the virus from entering host cells, making it a promising candidate for developing new antiviral therapies against SFTSV.
Improved detection of Zika virus RNA in human and animal specimens by a novel, highly sensitive and specific real-time RT-PCR assay targeting the 5'-untranslated region of Zika virus.
Jasper Fuk-Woo Chan Cyril Chik-Yan Yip Kah-Meng Tee Zheng Zhu Jessica Oi-Ling Tsang Terance Gi-Wai Tsang
Trop Med Int Health
May 2017
Objective And Method: We developed and evaluated five novel real-time RT-PCR assays targeting conserved regions in the 5'-untranslated region (5'-UTR), envelope (E'), non-structural protein 2A (NS2A), NS5 and 3'-UTR of the ZIKV genome.
Results: The ZIKV-5'-UTR assay exhibited the lowest in vitro limit of detection (5-10 RNA copies/reaction and 3.0 × 10 plaque-forming units/ml).