Publications by authors named "Teppo Stenholm"

Article Synopsis
  • The research focused on finding ways to differentiate between mild small bowel Crohn's disease (CD) and functional gastrointestinal disorders like irritable bowel syndrome (IBS) without needing invasive procedures such as small bowel capsule endoscopy (SBCE).
  • A retrospective analysis of 374 patients showed that fecal calprotectin (FC), serum albumin, and ESR were significant indicators of small bowel CD, while Hb and CRP were not.
  • The study concluded that using a CECDAI-score of 3 and considering FC levels below 50 ug/g could help predict small bowel CD, suggesting that FC testing could be a useful preliminary step before SBCE in certain patients.
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Background: We present here the first application of 2-photon excited fluorescence detection (TPX) technology for the direct screening of clinical colonization samples for methicillin-resistant Staphylococcus aureus (MRSA).

Methods: A total of 125 samples from 14 patients with previously identified MRSA carriage and 16 controls from low-prevalence settings were examined.

Results: The results were compared to those obtained by both standard phenotypic and molecular methods.

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Rapid, high-throughput screening tools are needed to contain the spread of hospital-acquired methicillin (meticillin)-resistant Staphylococcus aureus (MRSA) strains. Most techniques used in current clinical practice still require time-consuming culture for primary isolation of the microbe. We present a new phenotypic assay for MRSA screening.

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Development of a new phenotypic technique for rapid antimicrobial susceptibility testing (AST) of methicillin-resistant Staphylococcus aureus is presented. The new technique combines bacterial culturing and specific immunometric detection in a single separation-free process. The technique uses dry chemistry reagents and the recently developed two-photon excitation detection technology, which allows online detection of bacterium-specific growth.

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