[Alzheimer disease and epilepsy].

Alzheimer Disease (AD) is a progressive neurodegenerative disorder characterized by loss of memory, difficulty in thinking, changes in behavior and personality disorders. The risk of developing epileptic seizures (ES) in patients with AD increases significantly. Animal and human studies have shown a close relationship between the pathogenesis of ES and AD.

[Long-term EEG monitoring in patients with acute traumatic brain injury].

Objective: To investigate the informativeness of long-term scalp EEG monitoring in patients with acute traumatic brain injury (TBI).

Material And Methods: The informativity of long-term EEG monitoring (LTM) was performed in 60 patients with acute severe TBI. Odd ratios (OR) of unfavorable outcome and non-convulsive status epilepticus (NCSE) among clinical, neurophysiological and radiological features were calculated.

[Posttraumatic seizures: a prospective cohort study].

Aim: To evaluate the incidence and risk factors for posttraumatic seizures (PTS).

Material And Methods: The authors conducted a prospective study of 237 patients with TBI of varying severity. The patients were hospitalized and examined in Moscow neurosurgery departments.

[Patterns of brain functional connectivity in frontal and temporal lobe epilepsies].

Aim: To examine alterations of functional connectivity (FC) of the brain in patients with frontal and temporal lobe epilepsies.

Material And Methods: Forty-three patients, aged 18-55 years, including 32 with temporal lobe epilepsy (TLE) and 11 with frontal lobe epilepsy (FLE), and 32 age/gender-matched healthy controls (HC) underwent structural and functional MRI on 1,5 T scanner. Imaging data were further analysed for functional connectivity characteristics by seed-based and ICA analyses.

[Subcortical laminar heterotopia 'double cortex syndrome'].

This article presents a clinical case of a 29-year-old patient with 'Double cortex syndrome' with epilepsy, intellectual and mental disorders. Subcortical band heterotopia is a rare disorder of neuronal migration. Such patients typically present with epilepsy and variable degrees of mental retardation and behavioral and intellectual disturbances.

[Neuronet restructuring in focal and generalized epilepsy according to resting state fMRI].

Aim: To compare neuronet restructuring in focal and generalized epilepsy.

Material And Methods: Seventy-seven patients, aged from 18 to 65 years, with the diagnosis of epilepsy, including 63 patients with focal epilepsy and 14 with generalized epilepsy, were examined. A control group included 23 healthy people.