D-Dimer, ferritin, and lactate dehydrogenase (LDH) as predictors of mortality in hospitalized COVID-19 patients.

Introduction: Several laboratory parameters may be predictors of coronavirus disease 2019 (COVID-19) mortality. This study aimed to analyze the potential of D-dimer, ferritin, and lactate dehydrogenase (LDH) to predict mortality in severe COVID-19 patients.

Methodology: A retrospective cohort study, including 147 patients, was examined using secondary data from medical records of hospitalized COVID-19 patients.

Correlation of serum interleukin-6 levels and neutrophil-lymphocyte ratio in the severity of COVID-19.

Interleukin-6 (IL-6) is a pro-inflammatory cytokine that is produced at varying levels in patients with coronavirus disease 2019 (COVID-19). The neutrophil-lymphocyte ratio (NLR) is one of the new inflammatory markers of COVID-19. This study aimed to evaluate the differences in IL-6 level and the NLR in mild and severe COVID-19 and assess their correlation with COVID-19 severity and the correlation of IL-6 and NLR in COVID-19.

Glycemic control as the main determinant factor of serum VEGF levels in type 2 diabetes mellitus patients.

Diabetes mellitus (DM) is a main endocrine disorder that may cause vascular complications as the disease progresses. Vascular endothelial growth factor (VEGF) has been linked to the development of micro and macrovascular diabetic complications. This study aimed to assess several factors including blood pressure, body mass index, lipid profile, kidney function, and glycemic control that may provide the rise of serum VEGF levels in type 2 DM subjects.

Anthropometric features in predicting insulin resistance among non-menopausal Indonesian adult females.

Introduction: The prevalence of obesity is increasing worldwide in high, low, and middle-income countries such as Indonesia. Obesity rate is higher in females in Indonesia. Obesity has important contribution in the occurrence of insulin resistance (IR) and type 2 diabetes mellitus.

OPA1 gene mutations in Japanese patients with bilateral optic atrophy unassociated with mitochondrial DNA mutations at nt 11778, 3460, and 14484.

Purpose: To report mutations in the OPA1 gene in Japanese patients with bilateral optic atrophy unassociated with mitochondrial DNA mutations at nt 11778, 3460, and 14484.

Methods: Twelve unrelated patients with bilateral optic atrophy and 100 healthy controls were examined. Each exon of the OPA1 gene was amplified by polymerase chain reaction (PCR).