Safflower extract inhibiting apoptosis by inducing autophagy in myocardium derived H9C2 cell.

The Heart failure (HF) is considered as the end-stage of various heart disease and associated with high mortality globally. Progressive loss of cardiac myocytes via apoptosis is considered as the most important factor for HF pathology. In this study, we demonstrated that Safflower extract was able to inhibitthe apoptosis inducted by Angiotensin II (AngII) in a ratmyocardium derived cell line H9C2.

Compact large area and high-quality Au film with a hierarchical structure and its application in SERS.

We have described a novel and facile strategy for fabricating a compact large area and high-quality Au film with a hierarchical structure (HS) by using a polyaniline slice as a reductant. The unique morphology of the as-prepared Au HS film, which is controlled by the concentration of AuCl4(-), results in enhanced Raman signals toward probe molecules such as 4-aminothiophenol (4-ATP), 2-naphthalenethiol (2-NAT) and 4-mercaptobenzoic acid (4-MBA). The employed approach may shed some light on simultaneously fabricating and immobilizing unique Au micro/nanostructures.