Regulating the work function and surface hydrophobicity of an indium tin oxide electrode for enhanced electrochemiluminescence analysis.

The electrochemical properties of the indium tin oxide (ITO) electrode were improved significantly by surface modification with ethephon and an ultrathin polydimethylsiloxane (PDMS) layer to regulate the work function and surface hydrophobicity of ITO. Based on this strategy, the electrochemiluminescence (ECL) intensity of tris(2,2'-bipyridyl)ruthenium (Ru(bpy)) and tri--propylamine (TPrA) in solution and on a microbead surface can be enhanced by 110 and 2 times, respectively. When using the modified electrode to detect nicotinamide adenine dinucleotide (NADH), the linear range (5-1000 μM) was increased dramatically in comparison with a bare ITO electrode, with a limit of detection of 1.

Tuning the D-Band Center of BiS─MoS Heterostructure Towards Superior Lithium-Sulfur Batteries.

Lithium-sulfur (Li-S) batteries are one of the most promising energy storage devices due to their environmental friendliness, low cost, and high specific capacity. However, the slow electrochemical kinetics and the "shuttle effect" have seriously hindered their commercialization. Herein, the nanoflower BiS─MoS (BMS) heterostructure is synthesized by a two-step hydrothermal method, and then the BiS─MoS-Polypropylene (BMS-PP) interlayer is constructed.

Genome-Wide Identification of Calmodulin-Binding Protein 60 Gene Family and the Function of in Cotton Growth and Development and Abiotic Stress Response.

The calmodulin-binding protein 60 () family is a gene family unique to plants, and its members play a crucial role in plant defense responses to pathogens and growth and development. Considering that cotton is the primary source of natural cotton textile fiber, the functional study of its gene family members is critical. In this research, we successfully identified 162 members from the genomes of 21 species.

Comprehensive identification and functional characterization of GhpPLA gene family in reproductive organ development.

Background: Phospholipases As (PLAs) are acyl hydrolases that catalyze the release of free fatty acids in phospholipids and play multiple functions in plant growth and development. The three families of PLAs are: PLA1, PLA2 (sPLA), and patatin-related PLA (pPLA). The diverse functions that pPLAs play in the growth and development of a broad range of plants have been demonstrated by prior studies.

Characteristic of GEX1 genes reveals the essential roles for reproduction in cotton.

GEX1 (gamete expressed 1) proteins are critical membrane proteins conserved among flowering plants that are involved in the nuclear fusion and embryonic development. Herein, we identified the 32 GEX1 proteins from representative land plants. In cotton, GEX1 genes expressed in various tissues across all stages of the life cycle, especially in pollen.

GhCKX14 responding to drought stress by modulating antioxi-dative enzyme activity in Gossypium hirsutum compared to CKX family genes.

Background: Cytokinin oxidase/dehydrogenase (CKX) plays a vital role in response to abiotic stress through modulating the antioxidant enzyme activities. Nevertheless, the biological function of the CKX gene family has yet to be reported in cotton.

Result: In this study, a total of 27 GhCKXs were identified by the genome-wide investigation and distributed across 18 chromosomes.

Evolutionary Relationships and Divergence of Gene Family Involved in Development and Stress in Cotton ( L.).

Filamin protein is characterized by an N-terminal actin-binding domain that is followed by 24 Ig (immunoglobulin)-like repeats, which act as hubs for interactions with a variety of proteins. In humans, this family has been found to be involved in cancer cell invasion and metastasis and can be involved in a variety of growth signal transduction processes, but it is less studied in plants. Therefore, in this study, 54 gene family members from 23 plant species were investigated and divided into two subfamilies: FLMN and GEX2.

Identification, Classification and Characterization Analysis of Gene in Cotton.

(), Leucine-rich repeats in F-box proteins, belongs to the Skp1-Cullin1-F-box protein (SCF) E3 ligase family. genes play important roles in plant growth, such as plant hormones, responses to environmental stress, and floral organ development. Here, a total of 518 genes were identified and analyzed in six plant species.

Expression Patterns Divergence of Reciprocal F Hybrids Between and Reveals Overdominance Mediating Interspecific Biomass Heterosis.

Hybrid breeding has provided an impetus to the process and achievement of a higher yield and quality of crops. Interspecific hybridization is critical for resolving parental genetic diversity bottleneck problems. The reciprocal interspecific hybrids and their parents ( and ) have been applied in this study to elucidate the transcription regulatory mechanism of early biomass heterosis.

Characterization and Functional Analysis of , A NAM Domain Gene, Coordinates the Leaf Senescence in Upland Cotton ( L.).

In the process of growth and development, cotton exhibits premature senescence under various abiotic stresses, impairing yield and fiber quality. NAC (NAM, ATAF1,2, and CUC2) protein widely distributed in land plants, play the critical role in responding to abiotic stress and regulating leaf senescence. We have identified and functional analyzed a NAM domain gene in upland cotton, it was located on the A11 chromosome 4,921,702 to 4,922,748 bp, only containing one exon.

Genome-wide Characterization of the JmjC Domain-Containing Histone Demethylase Gene Family Reveals GhJMJ24 and GhJMJ49 Involving in Somatic Embryogenesis Process in Cotton.

The Jumonji C (JmjC) domain-containing protein family, an important family of histone demethylase in plants, can directly reverse histone methylation and play important roles in various growth and development processes. In the present study, 51 genes () were identified by genome-wide analysis in upland cotton (), which can be categorized into six distinct groups by phylogenetic analysis. Extensive syntenic relationship events were found between and .

In Situ Electrochemical Activation Derived Li MoO Nanorods as the Multifunctional Interlayer for Fast Kinetics Li-S batteries.

Li-S batteries (LSBs) have attracted worldwide attention owing to their characteristics of high theoretical energy density and low cost. However, the commercial promotion of LSBs is hindered by the irreversible capacity decay and short cycling life caused by the shuttle effect of lithium-polysulfides (LiPSs). Herein, a hybrid interlayer consisting of MoO , conductive Ni foam, and Super P is prepared to prevent the shuttle effect and catalyze the LiPSs conversion.

Application of Adaptive MOMEDA with Iterative Autocorrelation to Enhance Weak Features of Hoist Bearings.

Low-speed hoist bearings are characterized by fault features that are weak and difficult to extract. Multipoint optimal minimum entropy deconvolution adjusted (MOMEDA) is an effective method for extracting periodic pulses in a signal. However, the decomposition effect of MOMEDA largely depends on the selected pulse period and filter length.

Differentiation in the genetic basis of stem trichome development between cultivated tetraploid cotton species.

Background: Cotton stem trichomes and seed fibers are each single celled structures formed by protrusions of epidermal cells, and were found sharing the overlapping molecular mechanism. Compared with fibers, cotton stem trichomes are more easily observed, but the molecular mechanisms underlying their development are still poorly understood.

Results: In this study, Gossypium hirsutum (Gh) and G.

Application of ICEEMDAN Energy Entropy and AFSA-SVM for Fault Diagnosis of Hoist Sheave Bearing.

The mine hoist sheave bearing is a large heavy-duty bearing, located in a derrick of tens of meters. Aiming at the difficulty of sheave bearing fault diagnosis, a combined fault-diagnosis method based on the improved complete ensemble EMD (ICEEMDAN) energy entropy and support vector machine (SVM) optimized by artificial fish swarm algorithm (AFSA) was proposed. Different location of the bearing defect will result in different frequency components and different amplitude energy of the frequency.

1,25(OH)2D3 Attenuates IL-1β-Induced Epithelial-to-Mesenchymal Transition Through Inhibiting the Expression of lncTCF7.

The activated form of vitamin D3, 1,25-dihydroxyvitamin D3 [1,25(OH)2D3], regulates numerous cellular processes, including inhibition of cancer progression. IL-1β has been reported to facilitate cancer development, especially by inducing an epithelial-to-mesenchymal transition (EMT) in several malignant tumors. However, the underlying mechanism of 1,25(OH)2D3 and IL-1β in colorectal cancer (CRC) still remains largely unknown.

Application of Mutual Information-Sample Entropy Based MED-ICEEMDAN De-Noising Scheme for Weak Fault Diagnosis of Hoist Bearing.

In this paper, a novel weak fault features extraction scheme is proposed to extract weak fault features in head sheave bearings of floor-type multi-rope friction mine hoists in strong noise environments. A mutual information-based sample entropy (MI-SE) is proposed to select the effective intrinsic mode function (IMF). The numerical simulation presented in this paper has demonstrated that the improved complete ensemble empirical mode decomposition with adaptive noise (ICEEMDAN) has a poor performance on weak signals processing under a strong noise background, and fault features cannot be identified clearly.

Activated gastric cancer-associated fibroblasts contribute to the malignant phenotype and 5-FU resistance via paracrine action in gastric cancer.

Background: Cancer-associated fibroblasts (CAFs) play important roles in tumor progression. However, the behaviors of activated CAFs in gastric cancer remain to be determined. The aim of the present study was to investigate the correlations between activated gastric CAFs and the prognosis of patients with gastric cancer, and to determine the effects of activated CAFs on the malignant phenotype and 5-fluorouracil resistance in this cancer.

Splenic artery embolization with detachable balloons for hypersplenism.

Objective This study was performed to investigate the efficacy of proximal splenic artery embolization using detachable balloons for patients with hypersplenism and portal hypertension. Methods Twelve patients diagnosed with hypersplenism with thrombocytopenia or leukocytopenia caused by portal hypertension were treated by proximal splenic artery embolization with detachable balloons and metallic fibered coils. All patients were followed for up to 6 months.

Long non-coding RNA lncTCF7 activates the Wnt/β-catenin pathway to promote metastasis and invasion in colorectal cancer.

Long non-coding RNA (Lnc)TCF7 is a novel lncRNA that is involved in tumorigenesis. Previous studies have revealed that lncTCF7 serves an essential role in maintaining cancer stem cell self-renewal; however, the functions of lncTCF7 in colorectal cancer (CRC) remain unknown. Therefore, the present study aimed to investigate the role of lncTCF7 in CRC.

Overexpression of long non-coding RNA colon cancer-associated transcript 2 is associated with advanced tumor progression and poor prognosis in patients with colorectal cancer.

The aim of the present study was to explore the clinicopathological and prognostic significance of long non-coding RNA (lncRNA) colon cancer-associated transcript 2 (CCAT2) expression in human colorectal cancer (CRC). Expression levels of lncRNA CCAT2 in CRC, adjacent non-tumor and healthy colon mucosa tissues were detected by quantitative polymerase chain reaction. The disease-free survival and overall survival rates were evaluated using the Kaplan-Meier method, and multivariate analysis was performed using Cox proportional hazard analysis.

H19 Overexpression Induces Resistance to 1,25(OH)2D3 by Targeting VDR Through miR-675-5p in Colon Cancer Cells.

The long noncoding (lnc) RNA H19 was involved in the tumorigenesis of many types of cancer. However, the role of H19 in the tumorigenesis of colon cancer has not been fully illustrated. Recent studies suggested a potential relationship between H19 and vitamin D receptor (VDR) signaling.

Effect of Long Noncoding RNA H19 Overexpression on Intestinal Barrier Function and Its Potential Role in the Pathogenesis of Ulcerative Colitis.

Background: Recently, long noncoding RNA (lncRNA) H19 has been reported to be related with VDR signaling and the development of inflammatory diseases including osteoarthritis. The aim of this study was to investigate the correlation between the expression level of H19 and VDR in ulcerative colitis (UC) tissues and to investigate the effect of H19 overexpression on intestinal epithelial barrier function.

Methods: The expression level of H19, miR-675-5p, and VDR in UC tissues and paired normal tissues collected from 12 patients with UC was investigated by quantitative real-time polymerase chain reaction.

GYY4137 ameliorates intestinal barrier injury in a mouse model of endotoxemia.

Intestinal barrier injury has been reported to play a vital role in the pathogenesis of endotoxemia. This study aimed to investigate the protective effect of GYY4137, a newly synthesized HS donor, on the intestinal barrier function in the context of endotoxemia both in vitro and in vivo. Caco-2 (a widely used human colon cancer cell line in the study of intestinal epithelial barrier function) monolayers incubated with lipopolysaccharide (LPS) or TNF-α/IFN-γ and a mouse model of endotoxemia were used in this study.

The Rho-mDia1 signaling pathway is required for cyclic strain-induced cytoskeletal rearrangement of human periodontal ligament cells.

Tooth movement is the result of periodontal tissue reconstruction. The biomechanical effects produced by orthopedic forces can affect the cytoskeletal rearrangement of human periodontal ligament cells (hPDLCs). However, the mechanisms responsible for the cytoskeletal rearrangement are not completely understood.