An Ultra-Stable 2D Linear Polymer Cathode for High-Performance Aqueous Zinc-Organic Batteries.

Two-dimensional structure of cathode materials possesses fast kinetics in aqueous zinc ion batteries. However, in organic linear polymers it is rare to form two-dimensional structures due to the bond rotations of the polymerization reaction. In this work, inspired by the process of forming carbon fibers from polyacrylonitrile, a novel two-dimensional linear polymer (2DLP) of poly(2H,11H-bis[l,4]triazino[3,2-b : 3',2'-m]triphenodithiazine-3,12-diyl-2,11-diyli-dene-11,12-bis[methyldene]) (PTL) cathode materials were prepared for aqueous zinc-ion battery cathode materials by designing ladder structure polymer molecules with highly restricted bond rotations.

Engineering Non-precious Trifunctional Cobalt-Based Electrocatalysts for Industrial Water Splitting and Ultra-High-Temperature Flexible Zinc-Air Battery.

Developing efficient, robust, and cost-effective trifunctional catalysts for the hydrogen evolution reaction (HER), oxygen evolution reaction (OER) and oxygen reduction reaction (ORR) at high current density and high temperature is crucial for water splitting at industry-level conditions and ultra-high-temperature Zinc-air battery (ZAB). Herein, cobalt nanoparticles well-integrated with nitrogen-doped porous carbon leaves (Co@NPCL) by direct annealing of core-shell bimetallic zeolite imidazolate frameworks is synthesized. Benefiting from the homogeneous distribution of metallic Co nanoparticles, the conductive porous carbon, and the doped N species, the as-fabricated Co@NPCL catalysts exhibit outstanding trifunctional performances with low overpotentials at 10 mA cm for HER (87 mV) and OER (276 mV), long-lasting lifetime of over 2000 h, and a high half-wave potential of 0.

Uniform Grown ZIF-L Layer for Suppressing Hydrogen Evolution and Homogenizing Zn Deposition in Aqueous Zn-Ion Batteries.

The hydrogen evolution and dendrite of Zn anode are the major troubles hindering the commercialization of aqueous Zn-ion batteries (AZIBs). ZIF-Ls, a typical metal-organic framework (MOF) with a highly ordered structure and abundant functional groups, seem to be the answer for the above bottlenecks. In this paper, a uniform ZIF-L layer was obtained on the Zn surface (Zn@ZIF-L) via an synthesis method to moderate the solvation structure of solid-liquid interface electrolyte reducing the contact between water and Zn, thereby relieving the hydrogen evolution and corrosion.

Identification of gene modules and hub genes in colon adenocarcinoma associated with pathological stage based on WGCNA analysis.

Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality in the world, in which colon adenocarcinoma (COAD) is the most common histological subtype of CRC. In this study, our aim is to identify gene modules and representative candidate biomarkers for clinical prognosis of patients with COAD, and help to predict prognosis and reveal the mechanisms of cancer progression. Weighted gene co-expression network analysis (WGCNA) was performed to construct a co-expression network and identify gene modules correlated with TNM clinical staging of COAD patients.

Analysis of differentially expressed circular RNAs for the identification of a coexpression RNA network and signature in colorectal cancer.

Circular RNAs (circRNAs) play an important regulatory role in tumorigenesis. The aim of the present study was to analyze the circRNA expression network and elucidate its potential implications in colorectal cancer (CRC). The circRNA expression profile was analyzed in CRC tissues by RNA sequencing, and the functions of differentially expressed genes were analyzed by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis.

FGF18 Enhances Migration and the Epithelial-Mesenchymal Transition in Breast Cancer by Regulating Akt/GSK3β/Β-Catenin Signaling.

Background/aims: Fibroblast growth factors (FGFs) and their high-affinity receptors contribute to autocrine and paracrine growth stimulation in several human malignant tumors, including breast cancer. However, the mechanisms underlying the carcinogenic actions of FGF18 remain unclear.

Methods: The transcription level of FGF18 under the hypoxic condition was detected with quantitative PCR (qPCR).

RNA sequencing and bioinformatics analysis of the long noncoding RNA-mRNA network in colorectal cancer.

Long noncoding RNA (lncRNA) plays an important regulatory role in tumorigenesis. This study aims to analyze the lncRNA-messenger RNA (mRNA) expression network and potential roles in colorectal cancer (CRC). The LncRNA expression profile was analyzed in CRC tissue by RNA sequencing and the functions of differentially expressed genes were analyzed by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG).

Sonic hedgehog-c-Jun N-terminal kinase-zinc finger protein Gli1 signaling protects against high glucose concentration-induced reactive oxygen species generation in human fibroblasts.

Diabetes mellitus (DM) complications affect patients and cause varying damage. Skin ulcers exhibit difficulties in wound healing, and the regulatory basis for this remains unclear. High glucose concentration (HG) was utilized to mimic DM in cultured cells.