Circ_0001666 upregulation promotes intestinal epithelial cell fibrosis in pediatric Crohn's disease via the SRSF1/BMP7 axis.

The epithelial-mesenchymal transition (EMT) is closely associated with Crohn's disease (CD) related intestinal fibrosis, a condition whose prevalence is increasing annually among children. Recently, the CD marker gene microarray screening revealed an upregulation of circ_0001666 in the colon tissues of CD patients, but its underlying mechanisms remain unclear. In this study, we explored the molecular mechanism of circ_0001666 in regulating EMT-mediated fibrosis in CD in vitro.

A new species and a new series of (Urticaceae) from south-western China.

The new series ElatostemasectionWeddellia series L.D. Duan & D.

[Establishment of Duplex PCR for Identifying Metagonimus yokogawai and Haplorchis taichui].

Objective: To develop a duplex PCR method for identifying Metagonimus yokogawai and Haplorchis taichui.

Methods: ITS1 sequences of M. yokogawai and H.