Introduction: Bronchoalveolar lavage (BAL) is frequently used in pulmonary medicine though it requires further optimization. Practical obstacles such as patient safety and procedural limitation have to date precluded large, controlled trials aimed at standardization of BAL procedure. Indeed, BAL guidelines are based on observational data.
View Article and Find Full Text PDFPrimary osteosarcomas of the jaw (OSJ) are rare, accounting for 6% of all osteosarcomas. This study aims to determine the value of SATB2 and MDM2 immunohistochemistry (IHC) in differentiating OSJ from other jawbone mimickers, such as benign fibro-osseous lesions (BFOLs) of the jaw or Ewing sarcoma of the jaw. Certain subsets of osteosarcoma harbor a supernumerary ring and/or giant marker chromosomes with amplification of the 12q13-15 region, including the murine double-minute type 2 (MDM2) and cyclin-dependent kinase 4 (CDK4) genes.
View Article and Find Full Text PDFEpithelioid hemangioendothelioma (EHE) is a rare vascular tumor with metastatic potential and estimated prevalence of less than one case per million. Among the musculoskeletal system, the long bones are commonly involved with approximately half patients experiencing multicentric involvement. Clinical course of EHE is often variable and nonspecific.
View Article and Find Full Text PDFWild bees are threatened by multiple interacting stressors, such as habitat loss, land use change, parasites, and pathogens. However, vineyards with vegetated inter-rows can offer high floral resources within viticultural landscapes and provide foraging and nesting habitats for wild bees. Here, we assess how vineyard management regimes (organic vs.
View Article and Find Full Text PDFPurpose: The aim of this study is to investigate the presence and prevalence of BRAF V600E mutation in ameloblastomas using anti-BRAF V600E monoclonal antibody (VE1 clone) and to identify any clinicopathologic correlation with BRAF V600E mutation in ameloblastoma.
Materials And Methods: The pathology files of the Department of Oral Pathology and Oral Medicine, Faculty of Dentistry, Lagos State University College of Medicine, Lagos, Nigeria, were searched for the diagnosis of ameloblastoma from 2016 to 2020. Archived non-decalcified formalin-fixed paraffin-embedded tissue underwent immunohistochemistry using anti-BRAF V600E antibody at the University of Pittsburgh, Pennsylvania.
Mountains influence species distribution through differing climate variables associated with increasing elevation. These factors determine species niche ranges and phenology. Although the distribution patterns of some specific insect groups relative to elevation have been determined, how differing environmental conditions across elevation zones differentially influence the phenology of various insect groups is largely unknown.
View Article and Find Full Text PDFBackground: Chronic Non-Infectious Osteomyelitis (CNO) is a chronic, relapsing, self-limiting inflammation of the bone. Although it is rare, CNO has been associated with inflammatory bowel disease and frequently precedes the initial diagnosis. We present a case of CNO in a patient with known ulcerative colitis in clinical remission who presented with purulent multifocal joint effusions in the setting of elevated inflammatory markers and fever suspicious for bacterial osteomyelitis.
View Article and Find Full Text PDFThe oribatid mite, Oppia nitens, has gained recognition in recent laboratory ecotoxicological tests, however, the species global distribution is limited to temperate regions and not ecologically relevant for tropical soils. The present study reports the first laboratory study aimed at assessing the ecotoxicity of contaminants with the tropical oribatid mite, Muliercula inexpectata. To develop the protocols, synchronized adult specimens of M.
View Article and Find Full Text PDFInteraction networks are sensitive to elevation gradients through changes in local distribution of interacting partners. Here, we use plant-pollinator interaction network metrics to assess the effect of elevation on flowers and flower-visiting insect assemblages on a sentinel mountain used for monitoring climate change in the flower- and insect-rich Cape Floristic Region. We also use these interaction metrics to explain the effect of environmental factors on the interaction networks.
View Article and Find Full Text PDFCo-flowering plant species commonly share flower visitors, and thus have the potential to influence each other's pollination. In this study we analysed 750 quantitative plant-pollinator networks from 28 studies representing diverse biomes worldwide. We show that the potential for one plant species to influence another indirectly via shared pollinators was greater for plants whose resources were more abundant (higher floral unit number and nectar sugar content) and more accessible.
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