Imidazole antifungal drug clotrimazole alters the behavior, brain acetylcholinesterase and oxidative stress biomarkers in African catfish Clarias gariepinus (Burchell 1822).

This study was carried out to determine the effect of clotrimazole (CTZ), an imidazole fungicide on behavior, brain acetylcholinesterase, lipid peroxidation and oxidative stress parameters in Clarias gariepinus juveniles. Fish were acutely exposed to five nominal concentrations of CTZ and control to assess the behavioral effects on fish. To determine the effects on brain acetylcholinesterase, lipid peroxidation and oxidative stress parameters, fish were exposed to three sub-lethal concentrations vis 7.

The Consequence of Aqueous Extract of Tobacco Leaves (. L) on Feed Intake, Body Mass, and Hematological Indices of Male Wistar Rats fed under Equal Environmental Conditions.

Objective: While the dangers of consuming tobacco by smoking has been of concern, the hazardous effect of other forms of tobacco consumption (in smokeless form) on health indices are less well explored. In this paper, we explored the effect of different doses of aqueous extract of tobacco leaves on feed intake, body mass, and hematological indices of male Wistar rats under equal environmental conditions.

Method: Using an oral route of administration, the rats (n = 24; w = 65-85 g; 2-3 weeks old) were administered at different doses of 100, 200, 400, 0 mg/kg body weight (b.

Morphological, haematological and biochemical changes in African catfish Clarias gariepinus (Burchell 1822) juveniles exposed to clotrimazole.

Clotrimazole (CLO) is an imidazole fungicide used in human and veterinary medicine for treating fungal infection. This study evaluated the changes in morphological, haematological and biochemical indices in Clarias gariepinus juveniles exposed to CLO. After the acute exposure, the 96 h LC value of CLO determined by probit analysis was 38.