Climate-based models for understanding and forecasting dengue epidemics.

Background: Dengue dynamics are driven by complex interactions between human-hosts, mosquito-vectors and viruses that are influenced by environmental and climatic factors. The objectives of this study were to analyze and model the relationships between climate, Aedes aegypti vectors and dengue outbreaks in Noumea (New Caledonia), and to provide an early warning system.

Methodology/principal Findings: Epidemiological and meteorological data were analyzed from 1971 to 2010 in Noumea.