Rapid Whole-Knee Quantification of Cartilage Using T, T, and T Mapping With Magnetic Resonance Fingerprinting.

Objective: Quantitative Magnetic Resonance Imaging (MRI) holds great promise for the early detection of cartilage deterioration. Here, a Magnetic Resonance Fingerprinting (MRF) framework is proposed for comprehensive and rapid quantification of T, T, and T with whole-knee coverage.

Methods: A MRF framework was developed to achieve quantification of Relaxation Along a Fictitious Field in the 2nd rotating frame of reference ( T) along with T and T.

Adiabatic spin-lock preparations enable robust in vivo cardiac T-mapping at 3T.

Magnetic Resonance Imaging (MRI) is the clinical gold standard for the assessment of myocardial viability but requires injection of exogenous gadolinium-based contrast agents. Recently, T-mapping has been proposed as a fully non-invasive alternative for imaging myocardial fibrosis without the need for contrast agent injection. However, its applicability at high fields is hindered by susceptibility to MRI system imperfections, such as inhomogeneities in the B and B fields.

Magnetic Resonance Imaging compatible Elastic Loading Mechanism (MELM): A minimal footprint device for MR imaging under load.

Quantitative Magnetic Resonance Imaging (MRI) can enable early diagnosis of knee cartilage damage if imaging is performed during the application of load. Mechanical loading via ropes, pulleys and suspended weights can be obstructive and require adaptations to the patient table. In this paper, a new lightweight MRI-compatible elastic loading mechanism is introduced.